中药脱痂膏对烧伤创面的作用  

The effect of Traditional Chinese Medicine Tuojiagao on burn wound

作　　者：俞为荣[1] 孙家玲[1] 陈玉林[1] 白刚[1] 王璐[1] 韦多[1] 戴方平[1] 刘世康[1] 葛绳德[1] 

机构地区：[1]第二军医大学长海医院烧伤科

出　　处：《第二军医大学学报》1999年第3期167-168,共2页Academic Journal of Second Military Medical University

摘　　要：目的：探讨外用中药脱痂膏对深度烧伤创面的脱痂机制。方法：取经脱痂膏和Ａｇ－ＳＤ霜换药的深Ⅱ度烧伤创面组织标本及渗液，用抗ＣＤ６８单抗标记深度烧伤创面组织中的巨噬细胞，并计数创面渗液细菌，比较两组间的差异。结果：使用脱痂膏的创面组织含有较多的ＣＤ６８＋细胞（巨噬细胞），而创面渗液细菌数量与Ａｇ－ＳＤ组无明显区别。结论：脱痂膏通过招引巨噬细胞至创面局部，吞噬和分解坏死组织，从而达到脱痂的目的。Objective: To study the mechanism of Traditional Chinese Medicine Tuojiagao in cleaning necrotic and denatured tissue in deep burn wound. Methods: Two groups of patients with deep burn wound were studied: (1) Traditional Chinese Medicine Tuojiagao group, (2) Ag SD frost group. Tissue and exudate of the wound were collected. Macrophages were marked with anti CD68 antibody in tissue slides. The bacteria of wound exudate were counted. Results: The sections from wounds after using Tuojiagao have more CD68 + cells (macrophages) than Ag SD group, and no difference of bacteria count was found between the 2 groups. Conclusion: Tuojiagao could clean necrotic tissue through recruiting macrophages to scavenge and break down it.

关 键 词：烧伤 脱痂膏 巨噬细胞 中医药疗法 

分 类 号：R269.440.5[医药卫生—中西医结合]