深静脉血栓形成急性期疗效的Meta分析  

Meta-analysis of acute results in deep venous thrombosis of lower extremities

作　　者：李锰[1] 高翔[1] 张彦荣[1] 蔡建辉[1] 

机构地区：[1]河北医科大学第二医院血管外科,石家庄050000

出　　处：《疑难病杂志》2010年第10期735-737,共3页Chinese Journal of Difficult and Complicated Cases

摘　　要：目的评价手术与溶栓治疗深静脉血栓形成的急性期疗效是否存在差异。方法检索Medline、PubMed、CMCC、Ovid以及中国知网(CNKI),检索年限均自建库到2007年3月,并追查所有纳入研究的参考文献。利用Revman 3.2统计软件对纳入相关文献的研究结果进行Meta分析。结果符合标准的文献10篇,Meta分析结果显示手术组急性期缓解率明显高于抗凝溶栓组[OR=3.62,95%CI(1.63,8.05)],肺栓塞的发生率差异无统计学意义(P>0.05)。结论手术治疗较溶栓治疗能更好地改善深静脉血栓形成的急性期临床表现,肺栓塞的发生率二者差异无统计学意义。Objective To evaluate the acute results of deep venous thrombosis（DVT） of lower extremities between venous thrombectomy and thrombolytic therapy.Methods Medline,PubMed,CMCC,Ovid and CNKI were searched and the references of eligible studies were manually seeked.Relative data was analyzed by Revman 3.2 software using fixed or random effect model to pool the OR.Results Fourteen RCTs were included（n = 1047）,ten of which adequately applied randomization.It was found by meta-analysis that,compared with the control group,in the operation group acute stage remission rate ascended[OR = 3.62,95%CI（1.63,8.05）];no difference was shown statistically in two groups in the possibility of pulmonary embolism during the period of treatment（P0.05）.Conclusion Compared with thrombolytic therapy,venous thrombectomy plus temporary arteriovenous fistula in acute DVT of lower extremities could improve clinical manifestation of early stage.

关 键 词：深静脉血栓形成 静脉取栓术 溶栓治疗 META分析 

分 类 号：R654.4[医药卫生—外科学]