158株肠球菌属的临床分布及耐药研究  

Clinical Species Distribution and Drug Resistance of 158 Isolates of Enterococcus

作　　者：陈迎晓[1] 江宇[1] 金小亚[1] 董培红[1] 石娜[1] 陈永平[1] 

机构地区：[1]温州医学院附属第一医院感染内科,浙江温州325000

出　　处：《中华医院感染学杂志》2010年第19期3047-3049,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解肠球菌属的临床分布特点及耐药状况,为临床合理用药提供依据。方法收集医院2009年4-6月常规培养检出的158株肠球菌属,分析其在各种临床标本中的分布特征和耐药状况。结果检出粪肠球菌61株(38.6%)、屎肠球菌40株(25.3%)、鹑鸡肠球菌28株(17.7%),铅黄肠球菌27株(17.1%)、鸟肠球菌2株(1.3%)、肠球菌属以泌尿系统和呼吸系统感染为主,其中尿液中检出71株(44.9%)、痰液中检出48株(30.4%);肠球菌属对四环素、利福平、莫西沙星、左氧氟沙星、庆大霉素的耐药率均>60.0%,检出耐万古霉素肠球菌2株,未发现耐利奈唑胺肠球菌。结论肠球菌属感染以粪肠球菌和屎肠球菌为主,鹑鸡肠球菌、铅黄肠球菌比例明显增加,肠球菌属可引起泌尿系统和呼吸系统等多部位感染;多药耐药和高耐药现象相当严重。OBJECTIVE To study the clinical species distribution and drug resistance of Enterococcus,so as to provide guidance to use antibiotics rationally in clinical therapy.METHODS Totally 158 isolates of Enterococcus were collected by cultured in normal methods in hospital from Apr to Jun 2009,and the characteristics of species distribution and drug sensibility were analyzed.RESULTS There were 61 E.faecalis（38.6%）,40 E.faecium（25.3%）,28 E.gallinarum（17.7%）,27 E.casselifavus and 2 E.avium（1.3%） strains.There were 71 Enerococcus strains（44.9%）isolated from urine and 48 strains（30.4%） from sputa.The drug resistance rate of Enterococcus to tetracycline,rifampin,moxifloxacin,levofloxacin,and gentamicin were more than 60.0%.In this study,2 strains of vancomycin resistant Enterococcus were found,while no linezolid resistant Enterococcus strain was isolated.CONCLUSIONS The urinary and the respiratory system are infected frequently by Enterococcus;E.faecalis and E.faecium are the main strains,the proportion of E.casselifavus and E.avium is increasing now.Enterococcus infection in hospitals is increasing year by year;the resistance rate of Enterococcus keeps on rising,and the pan-resistant strains are gradually increasing.

关 键 词：肠球菌属 临床分布 耐药性 

分 类 号：R378[医药卫生—病原生物学]