支原体快速培养与急性呼吸道感染的临床相关研究  

Rapid Cultivation of Mycoplasma pneumoniae and Acute Respiratory Infection

作　　者：马玲娣[1] 董燕芬[1] 程宝金[2] 范静[1] 王仕忠[1] 刘乾[1] 夏蕾[1] 

机构地区：[1]南京医科大学附属常州第二人民医院中心实验室,江苏常州213003 [2]南京医科大学附属常州第二人民医院中心儿科,江苏常州213003

出　　处：《中华医院感染学杂志》2010年第19期3074-3077,共4页Chinese Journal of Nosocomiology

摘　　要：目的探讨肺炎支原体(MP)快速培养法诊断急性呼吸道感染的临床价值及影响因素。方法 MP快速培养法检测咽拭子标本,被动凝集法检测血清MP抗体。结果 MP培养阳性率为女性略高于男性,3～5岁幼儿最高(54.05%);冬、春季的阳性率(40.02%、42.89%)显著高于夏秋两季;大环内酯类可部分降低其阳性率;两种方法检测MP感染的阳性率差异无统计学意义;发热、咳嗽、咳痰等临床上常见呼吸道感染症状不能作为MP感染的诊断指证。结论 MP快速培养可早期快速诊断急性呼吸道MP感染。OBJECTIVE To evaluate the clinical value of rapid culture of Mycoplasma pneumoniae（MP） in diagnosis of acute respiratory infection and explore the potential impact factors related to the MP rapid culture.METHODS The rapid MP culture was made for acute respiratory infections′ throat swabs,and passive agglutination detected serum MP antibody.RESULTS Female patients′ positive rate of MP cultivation was higher than males′.The positive rate of rapid MP cultivation for children aged 3-5 years was the highest（54.05%）.The positive rate of rapid MP cultivation in winter and spring was 40.02% and 42.89%,respectively,and obviously higher than that in summer and autumn.Macrolide antibiotics could reduce the MP culture positive rate,but there was no significant difference（P0.05）.Moreover,the positive rate of rapid culture for MP was in line with the rusults of serum of MP-Ab detection.No evidence was found between the common clinical signs such as fever,cough,expectoration and infection of MP,suggesting it can not be viewed as an independent index for diagnosis of MP infection.CONCLUSIONS The rapid MP culture plays a significant role in early rapid diagnosis of infection with MP.

关 键 词：肺炎支原体 快速培养 早期诊断 抗体检测 

分 类 号：R375[医药卫生—病原生物学]