联合疗法治疗面部激素依赖性皮炎临床观察  

To investigate the clinical efficacy and safety of the treatment of patients with facial steroid corticosteroid dependent dermatitis

作　　者：钱丽洁[1] 宁苏莉 徐东[1] 黄薏[1] 肖明[1] 

机构地区：[1]上海市第八人民医院,上海200235

出　　处：《中国医学工程》2010年第3期4-5,9,共3页China Medical Engineering

基　　金：上海市徐汇区卫生局科研基金资助项目(编号为SHXH2010012)

摘　　要：目的观察负离子冷喷加半导体激光后外用积雪苷软膏治疗面部糖皮质激素(以下简称激素)依赖性皮炎临床疗效和安全性。方法予实验组30例面部激素依赖性皮炎患者冷喷10min,半导体激光照射10min后外用积雪苷软膏,6d为1疗程,共4个疗程,前2疗程1/d次,后2个疗程为1次/2d,予对照组患者负离子冷喷,疗程同上。治疗后2周随访1次。结果停止治疗后2周后61.1%的患者疗效不变,红斑和脱屑的患者对治疗的反应较好,皮损为皮肤萎缩和毛细血管扩张治疗效应略差。结论此综合治疗方法治疗面部激素依赖性皮炎安全、有效。【Objective】To investigate the clinical efficacy and safety of the treatment of patients with facial steroid corticosteroid dependent dermatitis.【Methods】Thirty patients were treated with anion cold spray 10min,and with semiconductor laser10min and Jixuegan Shuang Cream,one course is 6 days,there is 24 days of the whole course of treatment,Once a day in the first weeks treatment,Once 2 days in the second weeks two treatment.Thirty patients of the group were treated with anion cold spray 10min only,the treatment is the same,Meanwhile the adverse events were observed.【Results】Marked effective rates were 61.1% in two weeks after the whole course of treatment.Among a variety of skin lesions,the therapeutic effect was better for erythema and scaly lesions than that for telangiectasia,inflammatory papules,and atrophic lesions.【Conclusion】The treatment may be a safe and effective treatment option for the patients with facial corticosteroid dependent dermatitis.

关 键 词：皮炎 激素依赖性 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]