急性心肌梗死病人血浆溶血磷脂酸与心脏重构的关系  

Patient with AMI of LPA in Blood Reference Cordis Reconstitution

作　　者：方居正 杨戈[2] 

机构地区：[1]河南平顶山市中医院,平顶山467000 [2]中国中医科学院广安门医院,北京100053

出　　处：《光明中医》2010年第10期1758-1759,共2页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：国家自然科学基金(No30672765/C190402);北京市自然科学基金(No7062058)

摘　　要：目的通过活血化瘀结合西药治疗冠心病心肌梗死,观察溶血磷脂酸(LPA)与心肌梗死心脏重构的关系,确定活血化瘀法对冠心病心肌梗死血管损伤的治疗作用。方法 70例病人随机分为对照组和血塞通胶囊治疗组,对照组采用纯西药,治疗组除西药外加用相应中成药活血化瘀,观察溶血磷脂酸治疗前后水平的变化。观察血浆溶血磷脂酸水平与心脏彩超左室舒张末内径的关系。结果对照组溶血磷脂酸水平治疗后较治疗组高,(0.01<P<0.05),但比治疗前低,(P<0.01),治疗组治疗后亦较治疗前低,(P<0.01)。采用统计学软件CS10.35计算后,两者明显正相关。结论加用活血化瘀中成药比单纯运用西药常规疗法降低血浆溶血磷脂酸水平效果明显,两种治疗方法均可通过降低溶血磷脂酸水平。经假设检验,心梗后血浆溶血磷脂酸水平与心脏彩超左室舒张末内径呈直线相关关系。Objective Through treatment AMI with activating blood circulation to dissipate blood stasis by traditional chinese drug and western medicine,we look into connection of LPA and AMI,appraise effect that activating blood circulation to dissipate blood stasis impact patient with AMI. Method 70 cases were divided into two groups at random,comparison group and therapy group. The former was only treated by western medicine,the latter was treated by both traditional chinese drug and western medicine,we judge the change of LPA level. Results The LPA level of comparison group is higher than therapy group,（0. 01 P 0. 05）; but it is lower than preceding therapy,（P 0. 01）,the therapy group is lower than preceding therapy too,（ P 0. 01 ）. CS10. 35 indicate ampho-correlation. Conclusion Activating blood circulation to dissipate blood stasis can manifest decline the level of LPA. Through hypothesis,the level of LPA in blood and cordis reconstitution are linear correlation.

关 键 词：直线相关 心肌梗死 溶血磷脂酸 

分 类 号：R542.22[医药卫生—心血管疾病]