北京社区超重及肥胖居民心血管病生物学危险因素聚集现状分析  

Prevalence of cardiovascular disease biological risk factor clustering among overweight and obese population in Beijing community—results from CCEIP

作　　者：傅媛媛[1] 余金明[2] 王家宏[3] 孙艺红[3] 刘会芳 胡大一[3] 

机构地区：[1]同济大学医学院,上海200092 [2]复旦大学公共卫生学院,上海200032 [3]北京大学人民医院心脏中心,北京100044 [4]北京市大兴区芦城卫生院,北京102600

出　　处：《中国实用内科杂志》2010年第10期904-906,共3页Chinese Journal of Practical Internal Medicine

基　　金：北京市科委科技攻关项目社区居民胆固醇教育和控制(D0906002040191)

摘　　要：目的分析北京社区超重及肥胖人群的心血管病生物学危险因素聚集情况。方法 2007年6月至8月对9786例"社区居民胆固醇教育及控制"项目受调查者资料进行分析。按体重指数(BMI)将受调查者分为正常体重、超重及肥胖3类人群;根据体格检查及晨起空腹血浆化验结果,评价3类人群心血管病生物学危险因素聚集情况。结果 (1)存在2个及2个以上生物学危险因素的个体分别占正常体重、超重及肥胖人群的10.5%、22.5%和37.9%,平均BMI每增加1,个体发生心血管病生物学危险因素聚集的风险增加21%。超重及肥胖男性患生物学危险因素聚集风险高于同BMI水平女性(P均<0.001);(2)青年、中年及老年男性肥胖者中,生物学危险因素聚集者所占比例为49.2%,49.7%和56.1%(P=0.285);上述3类女性肥胖者生物学危险因素聚集者所占比例分别为16.9%,35.7%和48.6%;(3)危险因素聚集组分最常见组合为"高血压+血脂异常",分别占男性超重和肥胖者的21.7%和38.7%,及女性超重及肥胖者的18.4%和25.5%。结论北京社区超重及肥胖者存在心血管病生物学危险因素聚集的风险明显高于正常体重人群;而在肥胖人群中,中青年男性与老年男性已具有相同危险性,故应将超重及肥胖人群,尤其是其中青年男性群体作为早期预防干预的重点对象,从而从上游预防心血管事件发生。Objective To investigate prevalence of CVD biological risk factor clustering among overweight and obese residents in Beijing community. Methods Cross-sectional data of 9786 subjects from CCEIP were obtained for analysis. Participants were divided into 3 groups （ Normal, overweight and obese population ） based on body mass index （BMI）. Body examinations were done to record blood pressure. Overnight fasting plasma samples were drawn to determinate blood lipid and glucose levels. Results （ 1 ） 10. 5% ,22. 5% and 37.9% subjects from normal, overweight and obese group had ≥ 2 biological CVD risk factors. The proportion of biological risk factor clustering patients elevated with the increase of BMI. Clustering hazard will increase by 21% when BMI increase every 1 unit. Clustering prevalence was higher in overweight and obese men than women （ both P 〈0. 001 ）. （2） Prevalence of clustering increased with aging in population. However, there was no significant difference among youth, middle aged and elderly obese male population （49. 2% , 49. 7% and 56. 1% , P = 0. 285 ）. （3）The most common clinical symptoms complex of clustering was hypertension and dyslipidemia. Conclusion The prevalence of CVD risk factor clustering was relatively high in overweight and obese population. Strengthen intervention should be taken in obese population, especially the young men, to prevent CVD events.

关 键 词：超重 高血压 血脂异常 

分 类 号：R5[医药卫生—内科学]