492例接触性皮炎患者斑贴试验分析  

Analysis of Patch Test Result of 492 Patients with Contact Dermatitis

作　　者：曹永艳[1] 闫鸣[1] 徐续玲[1] 陈红英[1] 

机构地区：[1]武汉市第一医院皮肤科,430000

出　　处：《中国医药指南》2010年第29期17-18,共2页Guide of China Medicine

摘　　要：目的明确临床常见变应原及各种变应原和性别的关系。方法采用"瑞敏"斑贴试验变应原中国筛查系列对492例疑诊接触性皮炎患者进行斑贴试验。结果斑贴试验总阳性率81.3%,男女斑贴试验阳性率无显著性差异(P<0.05)。常见致敏原依次为重铬酸钾、硫酸镍、卡巴混合物、氯化钴、芳香混合物、甲醛。8种变应原存在性别分布差异:男性阳性率显著高于女性的变应原有重铬酸钾、卡巴混合物、松香、亚乙基二胺和秋兰姆混合物;女性阳性率显著高于男性的有芳香混合物、对苯二胺基质、夸特15(P<0.05)。结论斑贴试验是帮助接触性皮炎患者寻找变应原的可靠方法。Objective To determine the frequent allgerns and the relationship between allergen and sex.Method 492 patients with suspected contact dermatitis carried out patch test of China standard series of allergens.Result The total positive rate of patch test is 81.3% and patch test positive rate for men and women is no difference.The allergens with high frequency are followed by potassium dichromate,nickel sulfate,carba mix,cobalt chloride,fragrance mix,formaldehyde.Eight kinds of allergens exist difference in the gender distribution：the allergens whose positive rates were significant higher in males than in females were potassium dichromate,carba mix,colophony,ethylene diamine and thiuram mix;the allergens sensitized females more frequently than males were fragrance mix,4-Phenylenediamine base and quaternium 15（P0.05）.Conclusion The patch test is a safe and effective way to seek the sentilizer for patients with contact dermatitis.

关 键 词：斑贴试验 接触性皮炎 变应原 

分 类 号：R758.22[医药卫生—皮肤病学与性病学]