致康胶囊对体内血栓形成的影响  

Effect of Zhikang Capsules on Thrombosis in Vivo

作　　者：李越[1] 刘梦洁[1] 刘静[1] 解恩义[1] 曹永孝[1] 

机构地区：[1]西安交通大学医学院药理学系,西安市710061

出　　处：《中国药房》2010年第39期3675-3677,共3页China Pharmacy

摘　　要：目的:研究致康胶囊对体内血栓形成的影响。方法:用角叉菜胶生理盐水溶液复制小鼠尾静脉血栓形成模型,用胶原蛋白-肾上腺素诱导小鼠脑血栓形成模型。结果:实验分为生理盐水、凝血酶和致康胶囊高、低剂量组。与生理盐水组比较,致康胶囊高、低剂量组的血栓发生率无显著差异;与生理盐水组比较,致康胶囊高、低剂量组小鼠死亡率无显著差异。结论:致康胶囊不增加体内血栓形成。OBJECTIVE：To study the effect of Zhikang capsules on thrombosis in vivo.METHODS：The mice caudal venous thrombosis model and cerebral thrombosis model were induced by carrageenan normal saline solution and collagen-adrenalin,respectively.RESULTS：Model mice were divided into NS group,thrombin group and Zhikang caupsule high-do-se and low-dose groups.Compared with NS group,the incidence of mice caudal venous thrombosis in Zhikang capsules high-dose and low-dose groups was not significant difference.Compared with NS group,mortality of model mice in Zhikang capsule high-dose and low-dose groups was not significant difference.CONCLUSION：Zhikang capsule doesn＇t induce thrombosis in vivo.

关 键 词：致康胶囊 血栓形成 小鼠 

分 类 号：R285.5[医药卫生—中药学] R97[医药卫生—中医学]