中西医结合治疗恢复期重型颅脑损伤98例  

Treatment of 98 Cases of Severe Traumatic Brain Injury in Recovery Stage by Integrative Chinese and Western Medicine

作　　者：王清平[1] 汝觅禄[1] 

机构地区：[1]甘肃省天水市第一人民医院神经外科,甘肃天水741000

出　　处：《上海中医药大学学报》2010年第5期46-48,共3页Academic Journal of Shanghai University of Traditional Chinese Medicine

摘　　要：目的:观察中西医结合治疗恢复期重型颅脑损伤的临床疗效。方法:采用随机对照试验方法,将196例重型颅脑损伤恢复期患者分为治疗组和对照组各98例,两组均采用西医常规疗法治疗,治疗组同时加用黄芪注射液和川芎嗪注射液静脉滴注。两组均治疗30d,随访6个月,观察临床疗效及神经功能缺损、相关生活质量指标的变化情况。结果:治疗后30d,治疗组愈显率为58.9%,伤残率为41.0%;对照组分别为44.2%、54.8%,两组愈显率和伤残率差异均有统计学意义(P<0.05)。6个月后随访,治疗组愈显率为78.7%,伤残率为20.2%;对照组分别为65.0%、34.0%,两组愈显率、伤残率比较差异均有统计学意义(P<0.05)。两组治疗前后神经功能缺损评分和GCS评分比较,差异有统计学意义(P<0.05);随访6个月后神经功能缺损评分和GCS评分与治疗前、治疗后比较,差异有统计学意义(P<0.05)。组间治疗后和随访6个月后比较,神经功能缺损评分、GCS评分差异均有统计学意义(P<0.05)。结论:西医常规疗法结合黄芪注射液和川芎嗪注射液可以明显改善重型颅脑损伤恢复期患者的神经功能,降低致残率,显著提高康复治疗效果。Objective：To observe the clinical efficacy of integrative Chinese and western medicine in the treatment of severe traumatic brain injury （TBI） in recovery stage. Methods： By the randomized and controlled method,196 subjects were divided into two groups： control group in which 98 cases were treated by conventional modality and treatment group in which 98 cases were treated by conventional modality,＂Huangqi Injection＂ and ＂Chuanxiongqin Injection＂,with a course of 30 days. The clinical effect was evaluated on 30th day and surveyed six months after treatment. Results： After 30-day treatment,the effective rate and morbidity rate were 58.9% and 41.0% in the treatment group; and they were respectively 44.2% and 54.8% in the control group,with striking differences between the two groups （P0.05）. Six-month survey showed that the effective rate and morbidity rate were 78.7% and 20.2% in the treatment group; and they were respectively 65.0% and 34.0% in the control group,with striking differences between the two groups （P0.05）. After treatment,the nerve deficit score and GCS were improved in both groups （P0.05）; and after six-month survey there were significant differences in the nerve deficit score and GCS compared with after and before treatment; after treatment and six-month survey there were significant differences in the nerve deficit score and GCS between treatment group and control group （P0.05）. Conclusion： Combined use of conventional modality,＂Huangqi Injection＂ and ＂Chuanxiongqin Injection＂ are effective to improve nerve function and reduce morbidity rate to treat severe TBI in recovery stage.

关 键 词：重型颅脑损伤 恢复期 中西医结合疗法 

分 类 号：R651.15[医药卫生—外科学]