子痫前期预测指标的筛选及应用价值  

Screening and estimating the application value of the high-risk factors in predicting preeclampsia.

作　　者：王琪[1] 张为远[1] 李阳[2] 张松[2] 杨益民[2] 

机构地区：[1]首都医科大学附属北京妇产医院,北京100026 [2]北京工业大学生命科学与生物工程学院

出　　处：《现代妇产科进展》2010年第9期652-654,共3页Progress in Obstetrics and Gynecology

基　　金：首都医学发展基金(No:2005-2011)

摘　　要：目的:筛选简便且实用的预测子痫前期的临床指标,并探讨这些指标预测子痫前期的应用价值。方法:回顾分析子痫前期患者危险因素,包括孕妇年龄、高血压家族史、流产史、孕产次、子痫前期史、工作种类及孕期水肿的发生,统计各指标与子痫前期发生的相互关系。结果:5项为子痫前期的高危因素,分别为:年龄≥35岁,高血压家族史,子痫前期史,经产妇,重体力劳动者。其中,子痫前期史结合水肿症状预测子痫前期,敏感性最高(50.0%),特异度达100%。结论:临床上可使用筛选出的指标,结合水肿症状预测,从而在亚临床阶段进行干预,减少重度子痫前期的发病率或控制在轻症阶段。Objectives：To explore simple and practical methods to predict preeclampsia,and their application value.Methods：We retrospectively investigated some risk factors of eclampsia,including age,the family history of hypertension,the miscarriage history,the gravidity and parity history,a history of preeclampsia,the type of work and the occurrence time of edema during pregnancy.Then analyzed the relationship between these factors and the occurrence of pre-eclampsia.Results：Five items were identified as high-risk factors of preeclampsia,including age≥35 years old,the positive family history of hypertension,the positive history of preeclampsia,the multipara woman,the heavy work during pregnancy.It is the best sensitivity（50.0%） of predicting preeclampsia by the positive history of preeclampsia with edema during pregnancy,and the specificity reach 100%.Conclusion：We can predict preeclampsia by the high risk factors combining with the symptom of edema,and carry out some measurements during the subclinical stage to reduce the occurrence of eclampsia.

关 键 词：子痫前期 预测 水肿 临床研究 

分 类 号：R714.244[医药卫生—妇产科学]