调脂降糖片治疗痰瘀互结型代谢综合征临床研究  

Clinical study on effect of "Tiaozhi Jiangtang Tablet" in treating metabolic syndrome of intermingled phlegm and blood stasis

作　　者：唐红[1] 宋秀玲[1] 宋怡萍[1] 

机构地区：[1]上海中医药大学附属龙华医院内分泌科,上海200032

出　　处：《上海中医药杂志》2010年第10期30-32,共3页Shanghai Journal of Traditional Chinese Medicine

摘　　要：目的观察调脂降糖片治疗痰瘀互结型代谢综合征的临床疗效。方法将60例痰瘀互结型代谢综合征患者随机分为两组,每组30例,除接受基础治疗外,治疗组予调脂降糖片、对照组予二甲双胍缓释片(泰白),疗程均为3个月。观察每组治疗前后空腹血糖(FPG)、糖化血红蛋白(HbA1c)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-c)、收缩压(SBP)、舒张压(DBP)、腰围(WC)、体质量指数(BMI)、中医证候的变化。结果治疗组HDL-c升高,TG、WC、中医证候积分降低,较对照组差异有统计学意义(P<0.01,P<0.05);两组降糖疗效差异无统计学意义(P>0.05)。结论调脂降糖片能显著改善痰瘀互结型代谢综合征患者脂代谢、糖代谢,降低体质量,并能改善中医证候。Objective To observe clinical effect of ＂Tiaozhi Jiangtang Tablet＂ in treating metabolic syndrome of intermingled phlegm and blood stasis.Methods Sixty subjects were randomly divided into treatment group and control group,30 cases in each group.The patients in the treatment group were treated with ＂Tiaozhi Jiangtang Tablet＂,and those in the control group received extended action tablet of metformin,with a course of three months.The levels of FPG,HbA1c,TG,HDL-c,SBP,DBP,WC,BMI and clinical symptom were observed.Results Compared with the control group,the levels of HDL-c increased;TG,WC and clinical symptom scores decreased in the treatment group（P〈0.05,P〈0.01）,but the effect on FPG and HbA1c had no significant difference between the two groups（P〈0.05）.Conclusion ＂Tiaozhi Jiangtang Tablet＂ can improve lipid and glucose metablism,and clinical symptoms of metabolic syndrome of intermingled phlegm and blood stasis.

关 键 词：代谢综合征 痰瘀互结 调脂降糖片 临床研究 

分 类 号：R259[医药卫生—中西医结合]