C12A7-O^-纳米材料的制备及抗菌活性  

Preparation and Bactericidal Activity of C12A7-O^-Nanoparticles

作　　者：宫璐[1] 沈静[1] 李全新[1] 

机构地区：[1]中国科学技术大学化学物理系,合肥230026

出　　处：《高等学校化学学报》2010年第10期1919-1923,共5页Chemical Journal of Chinese Universities

基　　金：国家"八六三"计划项目(批准号:2009AA05Z435);国家"九七三"计划项目(批准号:2007CB210206);国家自然科学基金(批准号:50772107)资助

摘　　要：利用溶胶-凝胶法制备了C12A7-O-{[Ca24Al28O64]4+·4(O-)}纳米材料.采用X射线衍射、电子顺磁共振及透射电子显微镜等手段对制备的材料进行了表征.结果表明,在最佳焙烧条件(1150℃,6h)下制备的材料平均粒径为74nm,并具有晶胞参数为(1.199±0.004)nm的C12A7(Ca12Al14O33)笼状结构,材料内包含浓度高达1.2×1020cm-3的氧负离子(O-).初步研究结果表明,合成的C12A7-O-纳米材料具有良好的广谱抗菌作用.C12A7-O-{ [Ca24Al28O64]4 ＋ ·4（O-） } nanoparticles were prepared by sol-gel method.The synthesized C12A7-O-nanoparticles were investigated by X-ray diffraction,electron spin resonance and transmission electron microscopy.The antibacterial test of the C12A7-O-nanoparticles was also performed against E.coli（DH5α）,S.aureus（ATCC 6538） and B.subtilis（ATCC 9372）.The results show that the best condition for preparing C12A7-O-nanoparticles was sintering at 1150 ℃ for 6 h in oxygen ambience.The mean particle size of the C12A7-O-nanoparticles was 74 nm,and the cell parameter of the C12A7（Ca12 Al14 O33） cage with a O-concentration of 1.2 × 1020 cm-3 was（1.199 ± 0.004） nm.The C12A7-O-nanoparticles also exhibited excellent broad-spectrum antibacterial activity.The unique features of present material such as thermal stability,environment-friendly property and safety,could be potentially utilized in antibacterial materials.

关 键 词：C12A7-O-纳米材料 溶胶-凝胶法 抗菌性能 

分 类 号：O614.231[理学—无机化学] O614.31[理学—化学]