复方苦参注射液对60例膀胱恶性肿瘤患者血液中CD4^+细胞计数影响的研究  

Effect of compound matrine injection on CD4^+ cell counts in 60 bladder carcinoma patients

作　　者：沙键[1] 

机构地区：[1]上海市徐汇区中心医院泌尿外科,上海200031

出　　处：《东南大学学报（医学版）》2010年第5期566-568,共3页Journal of Southeast University(Medical Science Edition)

摘　　要：目的:探讨复方苦参注射液对膀胱恶性肿瘤患者血液中CD4+细胞计数的影响。方法:对60例已确诊的膀胱恶性肿瘤患者,在传统治疗基础上加用复方苦参注射液30 ml.d-1。在注射前1周内、注射后3个月及注射后6个月,分别测定患者血液中CD4+细胞的绝对计数水平。结果:注射后3个月与注射前比较,患者血液中CD4+细胞绝对计数值差异无显著性(P>0.05);注射后6个月与注射前比较,差异有显著性(P<0.05)。结论:复方苦参注射液能增加膀胱肿瘤患者血液中CD4+细胞计数水平,提高机体免疫机能,改善生活质量。Objective： To investigate the effect of compound matrine injection on the changes of CD4＋ cells in 60 bladder carcinoma patients. Methods： 60 bladder carcinoma patients were treated with compound matrine injection（30 ml·d^-1 ）. The blood CD4＋ cell counts were respectively determined one week before injection, three months after injection and six months after injection. Results： Compared with those before injection, no significant changes of cell counts were found （ P 〉 0.05 ） three months after injection, but there were significant changes six months after injection（P 〈 0.05 ）. Conculsion： Compound matrine injection can increase the level of CD4＋ cell in bladder carcinoma patients.

关 键 词：复方苦参注射液 膀胱肿瘤 CD4+细胞 

分 类 号：R969[医药卫生—药理学] R737.14[医药卫生—药学]