细花线纹香茶菜的化学成分研究  

Chemical Constituents from Isodon lophanthoides var.graciliflora

作　　者：梁耀光[1] 徐新亚[1] 谢海辉[1] 林青[2] 魏孝义[1] 

机构地区：[1]中国科学院华南植物园,广州510650 [2]广州白云山和记黄埔中药有限公司,广州510515

出　　处：《热带亚热带植物学报》2010年第5期564-568,共5页Journal of Tropical and Subtropical Botany

基　　金：中国科学院知识创新工程重要方向项目(KSCX2-YW-R-218)资助

摘　　要：用色谱技术对细花线纹香茶菜(Isodon lophanthoides var.graciliflora)全草水提物进行分离纯化,获得了11种单体化合物。通过光谱分析及与文献数据对照,分别鉴定为牡荆素(vitexin,1)、藿香黄酮醇(pachypodol,2)、猫眼草黄素(chrysoplenetin,3)、9-羟基-5,7-豆甾二烯-4-酮(9-hydroxy-5,7-megastigmadien-4-one,4)、3,9-二羟基-5,7-豆甾二烯-4-酮(3,9-dihydroxy-5,7-megastigmadien-4-one,5)、黑麦草内酯(loliolide,6)、4-乙酰-5-甲基二氢呋喃-2-酮(4-acetyl-5-methyldihydrofuran-2-one,7)、5-羟甲基糠醛(5-hydroxymethylfuraldehyde,8)、5-甲氧甲基-1H-吡咯-2-甲醛(5-methoxymethyl-1H-pyrrole-2-carbaldehyde,9)、3-吲哚甲醛(indole-3-aldehyde,10)和丁二酸单丁酯(succini cacid monobutyl ester,11)。这些化合物均为首次从线纹香茶菜中分离得到。The aqueous extract from the whole plant of Isodon lophanthoides var. graciliflora was separated and purified by means of chromatographic technology and eleven compounds were isolated. On the basis of spectral data, they were identified as vitexin （1）, pachypodol （2）, chrysoplenetin （3）, 9-hydroxy-5,7-megastigmadien-4-one （4）, 3,9-dihydroxy-5,7-megastigmadien-4-one （5）, loliolide （6）, 4-acetyl-5-methyldihydrofuran-2-one （7）, 5-hydroxymethylfuraldehyde （8）, 5-methoxymethyl-1H-pyrrole-2-carbaldehyde （9）, indole-3-aldehyde （10）, and succinic acid monobutyl ester （11）. All the compounds were obtained from Isodon lophanthoides for the first time.

关 键 词：细花线纹香茶菜 黄酮 豆甾二烯-4-酮 呋喃内酯 

分 类 号：R284[医药卫生—中药学]