我院2009年铜绿假单胞菌感染分布与耐药性分析  

Analysis of the distribution and the drug resistance of P.aeruginosa in our hospital

作　　者：俞建[1] 王飞[1] 严伟[1] 

机构地区：[1]浙江省杭州市第一人民医院药剂科,杭州310006

出　　处：《中国卫生检验杂志》2010年第10期2514-2515,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解医院铜绿假单胞菌感染的分布与耐药情况。方法:采用VITEK-32微生物鉴定仪鉴定,纸片琼脂扩散法药敏试验进行统计分析。结果:全部铜绿假单胞菌株中痰液,尿液,血液和分泌物标本占93%,其中痰液60.9%、分泌物18.5%、尿液7.8%、血液5.8%。其敏感度高的是多粘菌素E(99.7%)、其次为阿米卡星(66.9%)、哌拉西林/他唑巴坦(61.2%)、庆大霉素(60.9%)、哌拉西林(60.3%)。结论:医院内铜绿假单胞菌耐药现象突出,临床应重视其流行情况并合理使用抗菌药物。Objective：To investigate the distribution and the drug resistance of P.aeruginosa in our hospital.Methods： The strains of P.aeruginosa isolated from clinical samples were identified by VITEK-32 system.Susceptibility test to antimicrobial agents was performed by disk diffusion methods.Results： 93% of total strains of P.aeruginosa were isolated from sputum,urine,blood and secretion samples,and 60.9% of them were isolated from sputum,18.5% from secretion samples,7.8% from urine,5.8% from blood.P.aeruginosa was most sensitive to polymyxin E（99.7%）,sensitive rate of amikacin was 66.9%,Piperacillin and tazobactam was 61.2%,Gentamicin was 60.9%,Piperacillin was 60.3%. Conclusion： Antimicrobial resistance of P.aeruginosa in our hospital is very prominent.It should be paid attention to the epidemic status of strains and rational use of antimicrobials agents in clinic.

关 键 词：铜绿假单胞菌 抗菌药物 耐药性 医院感染 

分 类 号：R378.991[医药卫生—病原生物学]