实时三维超声心动图评价原发性高血压患者左室重构的研究  

Quantification of Left Ventricular Remodeling in Patients with Essential Hypertention using Real-time Three-dimensional Echocardiography

作　　者：王敏[1] 郭盛兰[1] 王晓瑛[1] 覃诗耘[1] 陈敏华[1] 应康[1] 

机构地区：[1]广西医科大学第一附属医院超声科,南宁市530021

出　　处：《中国超声医学杂志》2010年第10期947-949,共3页Chinese Journal of Ultrasound in Medicine

基　　金：广西科学基金资助项目(No.桂科基0575061;No.桂科字0135041) ;广西卫生厅重点科研课题项目(No.卫生厅重200624)

摘　　要：目的应用实时三维超声心动图(RT-3DE)以评价原发性高血压左室重构患者左室功能及质量的情况。方法对30例正常人、30例无左室肥厚(NLVH)及33例高血压伴左室肥厚(LVH)患者进行常规二维超声检查及RT-3DE检查,测量左室质量指数(LVMI)、左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)及左室射血分数(LVEF)。同时,用组织多普勒(TDI)技术测量左室舒张功能参数Ea,Aa及Ea/Aa。结果 LVH组LVMI、LVEDV、LVESV明显高于NLVH组及正常对照组(P<0.05),而LVEF、Ea/Aa降低(P<0.05)。高血压病患者IVMI与LVEF呈负相关(r=-0.654,P<0.05)。LVH组LVEF低于大样本正常范围低值,但两者间差异无统计学意义。结论 RT-3DE可以评估原发性高血压病患者心脏的功能及结构。对于伴有心力衰竭的原发性高血压病患者,联合LVMI和LVEF进行评估左室收缩功能可能有更重要的临床意义。Objective To assess left ventricular volumes,function and quality in patients with essential hypertension using real time three dimensional echocardiography （RT-3DE）. Methods 63 patients with essential hypertension were divided into three groups：LVH,NLVH and 30 normal controls groups and under went two-dimensional echocardiography（2DE） and RT-3DE. Parameters including LVEF, LVEDV, LVESV, LVM and Ea/Aa were analyzed by echocardiography. Results Compared with control subjects and NLVH patients,LVEDV,LVESV and LVMI measured by RT-3DE increased in LVH patients（P〈0.05）while LVEF and Ea/Aa decreased （P〈0.05）. LVEF measured by RT 3DE correlated with LVMI in patients with essential hypertension （r= -0. 654,P〈0.05）. Conclusions RT-3DE is an important tool for the quantification of left cardiac performance and LVM in the patients with essential hypertension.

关 键 词：超声心动图描记术 实时三维 高血压 左室重构 

分 类 号：R540.45[医药卫生—心血管疾病] R544.1[医药卫生—内科学]