^(99m)Tc-MIBI硝酸异山梨酯介入显像对冠脉支架置入术后心肌血流灌注的评估  

Value of ^(99m)Tc-MIBI and its isosorbide dinitrate myocardial imaging on evaluated myocardial blood flow perfusion after intracoronary stenting

作　　者：宁尚峰[1] 黎川华[1] 

机构地区：[1]广西壮族自治区第二人民医院核医学科,广西桂林541002

出　　处：《心血管康复医学杂志》2010年第5期547-548,551,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨99m锝-甲氧基异丁基异腈(99mTc-methoxy isobutyl isonitrile,Tc-MIBI)评估冠状动脉支架置入术(支架置入术)后损伤区心肌细胞血流灌注状况的价值。方法::40例行支架置入术患者,分别在置入术前、后进行99mTc-MIBI心肌静态显像及其硝酸异山梨酯(ISDN)介入显像,对比分析损伤区心肌细胞血流灌注改善程度。结果:40例患者冠状动脉共有360个节段。术前Tc-MIBI ISDN介入显像异常109个节段(29.2%),显著少于Tc-MIBI静态显像异常的178个节段(49.4%,P<0.01)。支架置入术后ISDN介入显像异常91个(25.3%)节段也显著少于静态显像异常的112个节段(31.1%,P<0.05)。结论:99mTc-MIBI-ISDN介入显像较99mTc-MIBI心肌静态显像更能反映支架置入术后心肌血流灌注情况。Objective： To study the value of 99mTc--MIBI and its isosorbide dinitrate myocardial imaging on evaluated myocardial blood flow perfusion after intracoronary stenting. Methods： A total of 40 cases with 360 coronary seg- ments were study by 99mTc-- methoxy isobutyl isonitrile （99m Tc--MIBI） rest imaging and its isosorbide dinitrate （IS- DN） involving imaging before and after operation. The imaging of blood flow perfusion in myocardial cells between a- bove stated two methods. Results： Before intracoronary stenting, the abnormal segments were 109 （29.2%） in 99mTc --MIBI ISDN involving imaging, it was significantly less than that of 99m Tc--MIBI imaging during rest （178 seg- ments, 49.4%） ; after intracoronary stenting, the abnormal segments were 91 （25.3%） in 99mTc--MIBI ISDN invol- ving imaging, it was significantly less than that of 99mTc--MIBI imaging during rest （112 segments, 31.1%）, P〈 0.05 all. Conclusion： Fore reflect myocardial blood flow perfusion, 99mTc--MIBI ISDN involving imaging is better than 99mTc--MIBI myocardial rest imaging.

关 键 词：冠状动脉疾病 支架 放射性核素显像 

分 类 号：R541.409[医药卫生—心血管疾病]