2型糖尿病与心血管并发症研究新进展  

Latest Researches on Type 2 Diabetes Mellitus and Cardiovascular Complications

作　　者：南会兰[1] 张蕴[1] 

机构地区：[1]天津医科大学总医院干部病房,天津300052

出　　处：《医学综述》2010年第20期3142-3145,共4页Medical Recapitulate

摘　　要：2型糖尿病是一种严重危害人类健康的临床常见病。近年来,其心血管病并发症越来越得到重视。但是,目前对于其确切的发生机制及有效的预防和治疗措施仍不十分明确。强化降糖治疗对心血管并发症的影响仍有争议,但早期即刻降糖治疗获益得到肯定。糖基化终末产物及炎性反应、细胞因子在心血管并发症的发生发展中起到重要作用,或可为临床提供新的治疗方向。Diabetes mellitus is one of the most challenging health concerns of the 21st century,which is associated with a high risk of complications,especially cardiovascular events.But at present,the pathogenesis and effective prophylaxis or therapeutic regimens have not been founded.Tight glycemic control remains controversial,while early glycemic control benefits.Advanced glycation end products,vascular inflammation,and cytokines play critical role in the diabetes-associated atherosclerosis.

关 键 词：2型糖尿病 降糖治疗 糖基化终末产物 细胞因子 

分 类 号：R58[医药卫生—内分泌]