非糖尿病急性心肌梗死患者糖耐量异常对预后的影响  

Effect of Glucose Tolerance on Prognosis in Patients of Non-diabetic Acute Myocardial Infarction

作　　者：靳文军[1] 朱国英[1] 刘素梅[1] 吴晓炜[1] 尹义梅[1] 王献忠[1] 

机构地区：[1]邯郸市第一医院心血管科,河北邯郸056002

出　　处：《医学综述》2010年第20期3178-3179,共2页Medical Recapitulate

基　　金：邯郸市科学技术研究与发展计划资助课题(072317065)

摘　　要：目的探讨非糖尿病急性心肌梗死(AMI)患者不同糖耐量水平对预后的影响。方法将46例非糖尿病AMI患者分为糖耐量正常组21例和糖耐量异常组25例,统计两组患者肌酸激酶、天冬氨酸氨基转移酶、乳酸脱氢酶恢复时间,以及恶性心律失常、心力衰竭、心源性病死发生率的差异,观察1年内心绞痛积分和再次AMI发生率。结果与糖耐量正常组比较,糖耐量异常组患者肌酸激酶恢复时间明显延长,恶性心律失常、心绞痛积分和再次AMI发生率明显升高(P<0.05)。结论非糖尿病AMI糖耐量异常患者较之糖耐量正常者预后较差,控制AMI患者血糖水平,有利于改善预后。Objective To approach the effect of glucose tolerance on prognosis in patients of non-diabetic acute myocardial infarction（AMI）.Methods Fourty-six patients of non-diabetes AMI were divided into two groups randomly,namely normal glucose tolerance group（n= 21）and high glucose tolerance group（n= 25）,to observe the recovery time of creatine kinase（CK）,aspartate aminotransferase（AST）,lactate dehydrogenase（LDH）,the incidence rate of malignant arrhythmias,myocardial failure and cardiogenic mortality,the frequency of angina pectoris attacks,and the incidence rate of AMI recurrence in one year.Results Compared with the normal glucose tolerance group,the recovery time of CK,the incidence rate of malignant arrhythmias,the frequency of angina pectoris attacks and the incidence rate of AMI recurrence were increased in the high glucose tolerance group（P0.05）.Conclusion Compared with the normal glucose tolerance group,the high glucose tolerance of AMI patient were disadvantaged in their prognosis.The control of plasma glucose was helpful to improve the prognosis of AMI.

关 键 词：急性心肌梗死 糖耐量 预后 

分 类 号：R587.1[医药卫生—内分泌] R542.2[医药卫生—内科学]