一种苦杏仁苷提取物的制备方法  

One kind of method preparing amygdaloside extract from amygdala amara

作　　者：邓康颖[1] 谭晓梅[1] 罗佳波[1] 

机构地区：[1]南方医科大学中医药学院,广东广州510515

出　　处：《中华中医药学刊》2010年第10期2172-2174,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:研究苦杏仁中有效成分苦杏仁苷的最佳提取、精制方法。方法:采用正交实验法,以苦杏仁苷的含量为指标确定最佳提取条件;及不同结晶时间、乙醇用量对苦杏仁提取物精制的影响。结果:影响因素最大的是提取次数,其次是提取时间,再次是乙醇用量。最佳提取工艺确定为:6倍量95%乙醇提取2次,每次1h。所得粗品用无水乙醇(1∶30固液比)重结晶三次,得到含量为92.47%的苦杏仁苷纯品,苦杏仁苷转移率为45.92%。结论:此工艺步骤简单、经济可行,适用于苦杏仁苷的工业化生产。Objective：To study the optimum extraction and purification process for amygdaloside in amygdala amara.Methods：Using orthogonal design,optimal extracting technology was selected using the content of amygdaloside;and different crystallization time and dosage of alcohol for amygdaloside extract optimum purification.Results：The extraction times was the most effective factor,the second was the extraction time,and the last was the dosage of solution.The best extraction and purification process is 6 fold 95% alcohol,two times extraction and a hour each time.The crude amygdaloside is recrystallized by 30 fold alcohol three times to obtain 92.47% amygdaloside,yielding rate is 45.92%.Conclusion： The technology is suitable for industrial production.

关 键 词：苦杏仁苷 提取 结晶 工业化生产 

分 类 号：R285.5[医药卫生—中药学]