鸡大肠杆菌病多价蜂胶灭活疫苗研究(I报)——疫苗制备及免疫效力试验  

Studies on Polyvalent Propolis Inactivated Vaccine Ageuist Chicken E. coli──Preparation and effect test

作　　者：杨峻[1] 邵华斌[1] 刘泽文[1] 钱纪元[1] 黎秋华[1] 

机构地区：[1]湖北省农业科学院畜牧兽医研究所,430209

出　　处：《湖北畜牧兽医》1999年第3期9-12,共4页Hubei Journal of Animal and Veterinary Sciences

基　　金：湖北省农业科学院招标课题;湖北省重点科技研究项目

摘　　要：要研究以鸡大肠杆菌常见致病性血清型O_1、O_2、O_(78)3个血清型菌株制备成鸡大肠杆菌多价蜂胶灭活疫苗,以1ml/只免疫1月龄鸡,3周后攻毒保护车100%;每ml含10^(10)菌,10mg蜂胶佐剂的疫苗外观呈深褐,颗粒微小均匀,流动性好,使用方便;固体培养可获得大量抗原,简化浓缩工艺,其免疫效果明显好于液体培养菌疫苗.Three serotype strains of O1,O2andO78were made into polyvalent propolis inactivated vac-cine. The immune effect test proved: All chickens of a-month-old could be protected after three weekswhen they were vaccinated with 1 ml vaccine everyone.The physicial properties showed: The vaccine'scolour was deep brown, the pellet was vwry small and equal. The bactertial train test showed: solid trainvaccine could gain a great deal of Agent and immune effect was much better than the liquid train one.

关 键 词：鸡 大肠杆菌病 蜂胶灭活疫苗 疫苗 

分 类 号：S858.315.1[农业科学—临床兽医学]