山毛豆对小白鼠的亚慢性毒性试验研究  

Sdudy on Subchronic Toxicity Test of Tephrosia canadida DC. on Mice

作　　者：蔡小艳 赖志强 王士长[2] 蒋建生[2] 易显凤 韦锦益 梁永良 

机构地区：[1]广西畜牧研究所,南宁530001 [2]广西大学动物科学技术学院,南宁530003

出　　处：《中国畜牧兽医》2010年第10期39-42,共4页China Animal Husbandry & Veterinary Medicine

摘　　要：为开发山毛豆(Tephrosia canadida DC.)作为蛋白质饲料资源,进行了山毛豆亚慢性毒性试验,即在饲粮中用山毛豆叶粉替代20%、40%和60%的基础日粮饲喂小白鼠,对各组小白鼠的采食、生长、脏器系数及组织切片等指标进行了测定和分析。结果表明:①试验期间,小白鼠活动正常,对照组和试验组小白鼠都没有死亡;②试验组小白鼠的各脏器无明显肉眼可见剖检病变;③试验组小白鼠的各脏器系数与对照组差异不显著(P>0.05);④40%和60%试验组小白鼠肝脏、肾脏的组织形态发生轻微变化,其他脏器均正常。研究结果表明,山毛豆草粉可安全用于动物饲料中。In order to explore Tephrosia canadida DC.as a new kind of protein forage resource,sub chronic toxicity test of diet with Tephrosia canadida DC.of mice was carried out.The diets containing different proportions of Tephrosia canadida DC.powder were fed to mice,the intake condition,growth condition,organ coefficient and tissue slice were measured and analyzed.The results showed that：① In the course of the test,the mice were normal and there wete no mice dead in the control or test groups;②There was no pathological change in viscera,after mice of the test groups were killed;③Organ coefficients of mice were no significant difference（P0.05）between the control and test groups;④The liver and kidney tissue of mice in test group C（40%） and D（60%）changed slightly,while other viscera had no change.It indicated that Tephrosia canadida DC.could be safely used as animal forage.

关 键 词：山毛豆 亚慢性毒性试验 采食量 脏器系数 组织切片 

分 类 号：S859.82[农业科学—临床兽医学]