甜菜碱预防蛋鸡脂肪肝出血综合征的研究  

Study on the Effect of Betaine against Fatty Liver Hemorrhagic Syndrome in Laying Hens

作　　者：张彩英[1] 曹华斌[1] 胡国良[1] 郭小权[1] 曹洪峰[1] 黄爱民[1] 

机构地区：[1]江西农业大学动物科技学院,南昌330045

出　　处：《中国畜牧兽医》2010年第10期197-201,共5页China Animal Husbandry & Veterinary Medicine

基　　金：国家自然科学基金资助项目(3016006430760180);江西省自然科学基金资助项目(2007GZN0263)

摘　　要：本试验旨在研究甜菜碱对蛋鸡脂肪肝出血综合征的预防效果。选用300日龄海蓝褐蛋鸡120只,随机分为3组,每组4个重复,每个重复10只,在自由采食、饮水和光照16 h的条件下,分别饲喂正常日粮(代谢能11.30 MJ/kg,粗蛋白质17.20%)、高能量低蛋白质日粮(代谢能12.81 MJ/kg,粗蛋白质13.04%)和添加1000 mg/kg甜菜碱的高能量低蛋白质日粮60 d。于试验期第1、30、60天,每组取8只鸡采血制备血清和采集肝脏样品及腹脂,测定血脂含量、肝脂率和腹脂率,结合产蛋性能及病理学变化,综合判定脂肪肝出血综合征(fatty liver hemorrhagic syndrome,FLHS)的发生及甜菜碱的预防效果。结果表明,与对照组相比,饲喂高能量低蛋白质日粮30 d即可引发FLHS,饲喂60 d则病情进一步加重;而在高能量低蛋白质日粮中添加1000 mg/kg甜菜碱后,饲喂30 d时甜菜碱可显著抑制FLHS的发生,具有很好的预防作用,但饲喂60 d时甜菜碱的预防作用减弱。The experiment was conducted to investigate the effect of betaine against fatty liver hemorrhagic syndrome（FLHS） in laying hens.One hundred and twenty Hy-line brown laying hens at the age of 300 days were randomly assigned to 3 groups,with 4 replicate pens per group and 10 laying hens per pen,and a feeding experiment was conducted with them for 60 days.The laying hens were fed with either normal diet（ME 11.30 MJ/kg and CP 17.20%）,high energy-low protein diet（ME 12.81 MJ/kg and CP 13.04%） or the high energy-low protein diet plus 1000 mg/kg betaine.Feed and water were provided for ad libitum consumption and the birds received light of 16 h a day.Eight hens from each group were selected on 1st,30th,and 60th days to collect samples including serum,liver and abdominal fat,respectively.The concentration of serum lipids,rate of liver fat and abdominal fat,laying performance and histopathologic changes were investigated to determine the effect of betaine against FLHS.The results showed that compared with the control group,feed the laying hens with high energy-low protein diet for 30 days could induce FLHS,and feeding for 60 days could lead to severe FLHS.Compared with the high energy-low protein group,feed the laying hens with high energy-low protein diet plus 1000 mg/kg betaine for 30 days significantly prevent the inducion of FLHS,but its preventive effect decreased obviously after feeding for 60 days.

关 键 词：甜菜碱 蛋鸡 脂肪肝出血综合征 

分 类 号：S816.7[农业科学—饲料科学]