老年血液病患者医院侵袭性真菌感染的临床分析  

Analysis on clinical data of 120 senile hematological patients with nosocomial fungal infections

作　　者：胡明均[1] 李红[1] 李玉玲[1] 

机构地区：[1]郧阳医学院附属人民医院血液内科,湖北十堰442000

出　　处：《感染．炎症．修复》2010年第3期151-153,共3页Infection Inflammation Repair

摘　　要：目的:分析老年血液病患者医院侵袭性真菌感染的临床资料,为临床防治老年血液病患者医院真菌感染提供依据。方法:回顾性统计分析我院2006年11月1日-2009年12月31日收治的合并有医院真菌感染的120例老年血液病患者的临床资料。结果:120例老年血液病患者中,有105例合并慢性基础疾病,有108例1周前使用了广谱抗菌药物;在感染部位中,呼吸道感染占首位;在真菌培养结果中,白色念珠菌106株,占首位;早期诊断并给予适当治疗者的病死率为6.4%(7/110例);晚期诊断者的病死率为40.0%(4/10例)。结论:老年血液病合并医院侵袭性真菌感染患者多有慢性基础疾病和使用广谱抗菌药物的病史,病死率较高,对有相关病史的老年血液病患者应早期诊断早期治疗,减少病死率。Objective：To analyze the clinical data of 120 senile patients with hematopathy suffering from nosocomial fungal infections, and to provide basis for clinical prevention and treatment. Methods：The clinical data of 120 senile patients with hematopathy suffering from nosocomial fungal infections in our hospital from November 1, 2006 to December 31, 2009 were analyzed retrospectively. Results： Among the 120 cases, 105 were complicated with basic chronic illness, and 108 were treated with broad--spectrum antibiotics 1 week before the fungal infection. Respiratory tract was the main location of infection. There were 106 patients in whom Candlda albicans were isolated. The mortality was 6.4% （7/110 cases） for those with early diagnosis and proper treatment for such infection, 40.0% （4/10 cases） for those with delayed diagnosis. Conclusion： Senile hematological patients with nosocomial fungal infections were often complicated with basic chronic illness or with previous treatment with broadspectrum antibiotics, and the mortality is high. Early diagnosis is essential to reduce mortality.

关 键 词：老年血液病患者 真菌 医院感染 

分 类 号：R644[医药卫生—外科学]