酶联免疫吸附试验检测乙型肝炎病毒表面抗原的全面质量控制前后对比分析  

Comparative analysis of HBsAg detection by ELISA before and after comprehensive quality control

作　　者：顾友祥[1] 

机构地区：[1]江苏省泰州市职业技术学院医学技术学院,225300

出　　处：《检验医学与临床》2010年第20期2194-2195,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨建立全面质量控制体系对乙型肝炎表面抗原(HBsAg)酶联免疫吸附试验(ELISA)检测结果的影响。方法对未开展全面质量控制的2008年1～10月份2120例患者和全面开展质量控制后的2009年1～10月份2310例患者的HBsAg阳性率进行对比分析。结果 2008年前10个月阳性率为8.11%,而2009年前10个月阳性率为11.00%。两者比较,差异有统计学意义(χ2=10.239,P<0.001)。结论全面开展质量控制后,用ELISA法检测HBsAg其阳性率有了明显提高。Objective To explore the effect of establishment of a comprehensive quality control system on HBsAg detection results by ELISA assay.Methods The HBsAg positive rates detected by ELISA in 2120 cases before carrying out the comprehensive quality control from January to October in 2008 and 2310 case after carrying out the comprehensive quality control from January to October in 2009 were comparatively analyzed.Results Compared with positive rate of 2007,the positive rate was 8.11% in the first 10 months of 2008 and ll.00% in 2009 with the statistical significance（χ^2=10.239,P〈0.001）.Conclusion After carrying out the comprehensive quality control,the HBsAg positive rate using ELISA assay has improved markedly.

关 键 词：酶联免疫吸附试验 质量控制 乙型肝炎病毒 

分 类 号：R446[医药卫生—诊断学] R575.1[医药卫生—临床医学]