N,N’-双(1-苯基亚乙基)乙二亚胺及其类似物在低共熔物催化下的合成  

Synthesis of N,N'-bis(1-phenylethylidene)ethane-1,2-diamine and Its Analogues by Using DES as Catalyst

作　　者：陈梓湛[1] 李新军[2] 王翠翠[2] 邹新琢[2] 

机构地区：[1]上海应用技术学院化学与环境工程学院,上海200235 [2]华东师范大学化学系,上海200062

出　　处：《上海应用技术学院学报（自然科学版）》2010年第3期234-238,共5页Journal of Shanghai Institute of Technology: Natural Science

基　　金：上海市科委资助项目(073919106)

摘　　要：使用氯化胆碱与对甲苯磺酸配制成一种低共熔物,以此低共熔物为催化剂,甲苯为溶剂,加热反应1 h,成功制备了多个重要有机合成中间体——N,N’-双（1-苯基亚乙基）乙二亚胺及其类似物,产率为86%-94%。低共熔物可以至少重复利用5次。该反应过程具有快速、安全、简便、原料廉价等优点。A kind of deep eutectic solvent（DES） was prepared from choline chloride and p-TsOH.After the reaction mixture was heated for one hour,N,N＇-bis（1-phenylethylidene）ethane-1,2-diamine and its analogues were synthesized by using DES（choline chloride and p-TsOH） as catalyst and toluene as solvent and the yields of the products were 86%-94%.The DES was re-used at least five times.This process is rapid,safe,convenient and cheap.

关 键 词：氯化胆碱 低共熔物 N N’-双(1-苯基亚乙基)乙二亚胺 

分 类 号：TQ246.31[化学工程—有机化工]