微图形Ti-O薄膜亲水性对细胞行为的影响  

Effect of micro-patterned Ti-O thin film's wettability on adhesion behavior of endothelial cells and platelets in vitro

作　　者：陈江[1] 郭翔[1] 杨苹[1] 王锦标[1] 郑楠[1] 孙红[1] 黄楠[1] 

机构地区：[1]西南交通大学材料先进技术教育部重点实验室,四川成都610031

出　　处：《功能材料》2010年第10期1788-1791,共4页Journal of Functional Materials

基　　金：国家自然科学基金资助项目(30870629)

摘　　要：同时调控血小板和内皮细胞(ECs)的行为对心血管植入材料而言有着重要的意义。材料表面的亲水性和表面拓扑结构是影响细胞的粘附行为和形态的重要因素。采用光刻/湿法刻蚀及非平衡磁控溅射技术制备了微图形氧化钛薄膜,并通过紫外光照调控其亲水性,获得了亲/疏水间隔的微区,进而研究材料表面亲水性对血小板和内皮细胞粘附行为的影响。It is meaningful for the cardiovascular implants how to adjust the behavior of platelets and endothelial cells（ECs）simultaneously.Surface topology and wettability are suggested as the important factors influencing cell modality and adhesion behavior.In this paper,the wettability of micro-patterned Ti-O thin film was altered by UV irradiation to adjust adhesion behavior of platelets and ECs in vitro.

关 键 词：亲水性 微图形 Ti-O薄膜 血液相容性 紫外光照 

分 类 号：Q81[生物学—生物工程]