揉髌手法对兔膝关节软骨组织影响的实验研究  

The Study of the Rou-Bin Manipulation On Knee Joint Cartilage In Rabbit

作　　者：戴七一[1] 欧国建[1] 林光琪[2] 覃学流[1] 刘靖[2] 腾居赞[1] 朱江龙[1] 容向宾[1] 韩杰[1] 辛晓东[1] 袁经阳[1] 姚平[1] 

机构地区：[1]广西中医学院附属瑞康医院,广西南宁530011 [2]广西中医学院,广西南宁530001

出　　处：《辽宁中医杂志》2010年第10期2046-2047,I0001,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(30860359);广西科技厅自然基金资助项目(桂科自0832178)

摘　　要：目的:观察揉髌手法对兔膝关节软骨退变的影响。方法:随机将50只新西兰兔分为手法组、药物组、模型组、假模组和正常组,每组10只;前3组手术造成骨内高压型模型,假模组手术切口相同但不结扎、不切断相应血管,正常组不做任何处理。手法组每只兔揉髌手法治疗17次,药物组膝关节内注射玻璃酸钠注射液5次,其他兔无特殊处理。造模后12周末取所有兔右膝关节内侧胫骨平台软骨,HE染色,光镜观察软骨组织的变化。结果:假模组、正常组关节软骨无明显退变,模型组关节软骨退变明显,手法组、药物组关节软骨退变明显比模型组轻。结论:揉髌手法可明显延缓兔膝关节软骨组织的退变。Objective：To observe the influence of the Rou-Bin Manipulation on cartilage of knee joint in rabbit.Methods：50 New Zealand rabbits devided randomly into five gourps：Manipulation group,drug group,Model group,dummy-model group and the normal group,10 rabbits in each group;the first 3 groups cause IOH-model by operative,dummy-model group operate without damage the corresponding vessel,no treatment for the normal group.17 times of Rou-Bin manipulation on each rabbit in manipulation group,the rabbit injection with sodium hyaluronate 5 times in drug group,no special treatment for other rabbits.12 weeks after modeled,to take all the rabbit right knee medial tibial plateau cartilage tissue processing,observe the knee joint cartilage by light microscope after HE stained.Results：no obvious cartilage degeneration for dummy-model group and the normal group,cartilage degeneration in a serious for model group,Manipulation group and drug group degeneration lighter than model group.Conclusion：The Rou-Bin manipulation can significantly delay the degeneration of cartilage tissue of knee joint in rabbit.

关 键 词：手法 动物模型 膝关节 软骨组织 实验研究 

分 类 号：R244.1[医药卫生—针灸推拿学]