碳纳米管-TiO2修饰电极伏安法测定维生素K3  

Voltammetric determination of vitamin K_3 at carbon nanotubes-TiO_2composite film modified electrode

作　　者：卫应亮[1] 邵晨[2] 李超[2] 张路平[2] 孙刚[2] 张小平[3] 

机构地区：[1]洛阳理工学院环境工程与化学系,河南洛阳471023 [2]郑州轻工业学院材料与化学工程学院,河南郑州450002 [3]许昌学院文旅学院06旅本,河南许昌461500

出　　处：《化学研究与应用》2010年第10期1231-1235,共5页Chemical Research and Application

基　　金：国家自然科学基金项目(20871107)资助;河南省基础与前沿技术研究计划项目(072300420010)资助;河南省高等学校青年骨干教师资助计划项目(2009GGJS-123)

摘　　要：利用碳纳米管、二氧化钛两种纳米材料制成碳纳米管-TiO2复合膜修饰电极,进行了维生素K3电化学行为的研究。维生素K3在碳纳米管-TiO2复合膜修饰电极的电化学响应优于碳纳米管修饰电极,表明前者具有更好的催化作用。通过条件实验的优化,结果表明维生素K3在pH=9.42的氨水-NH4Cl底液中,富集时间为10s,富集电位于-0.60V,扫描速度为0.1V/s时有稳定的灵敏的氧化还原峰。峰电流与维生素K3浓度在3.0×10-6～8.0×10-5mol/L范围内呈良好的线性关系,检出限为5.0×10-7 mol/L。考查了修饰电极的重现性,5次平行测量的RSD为1.78%。该方法用于片剂药品中维生素K3含量的测定,回收率在97.5%～102%之间。In this paper,a novel nano-material composite film modified glassy carbon electrode（GCE） was developed based on mult-wall carbon-nanotube and nano-TiO2,and the electrochemical behavior of Vitamin k3（VK3） was investigated at this modified electrode.Compared with MWNTs electrode,the redox peaks current increased obviously at MWNTs-TiO2 modified electrode,which suggesting that this modified electrode showed excellent electrocatalytic activity for the redox of VK3.The experimental conditions were optimised,a couple redox peaks of VK3 was obtained under the conditions of pH = 9.42 NH3-NH4 Cl buffer solution,10s accumulation,accumulation potential at-0.60V,and 0.1V/s scanning speed.Under optimal conditions,A good linear relationship was found for VK3in the range of 3.0 × 10^-6 ～ 8.0 × 10^-5mol/L,and the detection limit was 5.0 × 10^-7 mol/L.The reproducibility of this modified electrode was also discussed.The relative standard deviation（RSD） value of measured peak currents was 1.78% with 5 parallel determinations.In addition,this proposed method was applied to the determination of VK3 in pharmaceutical tablets.The recoveries were found to be 97.5% ～ 102%,indicating that the accuracy of this method was good enough.

关 键 词：碳纳米管-TiO2复合修饰电极 维生素K3 伏安法 

分 类 号：O657.1[理学—分析化学]