随州市艾滋病病毒感染孕产妇母婴阻断的效果研究  

Study on Effectiveness of Blocking HIV Mother-to-infant Transmission in Suizhou

作　　者：郭芳[1] 周沛林[1] 金晓舟[1] 刘晓辉[1] 杨巍[1] 刘骏[1] 陈丽荣[1] 聂绍发[2] 

机构地区：[1]湖北省随州市疾病预防控制中心,湖北随州441300 [2]华中科技大学同济医学院公共卫生学院流行病与卫生统计学系

出　　处：《实用预防医学》2010年第10期1978-1980,共3页Practical Preventive Medicine

摘　　要：目的了解随州地区HIV阳性孕产妇中的婴幼儿感染HIV的状况,探讨减少及阻断HIV母婴垂直传播的方法,为预防和控制HIV母婴垂直传播提供一些依据。方法收集2002-2008年随州地区自愿咨询的HIV阳性孕产妇及所产婴幼儿,对2004年后的HIV阳性孕产妇及其新生儿实施综合干预。结果随州市2002-2008年共发现15例孕产妇为HIV阳性,2例幼儿HIV阳性,经母婴传播感染比例为0.34%(2/591),自然传播率为13.33%(2/15)。2004年7月实施母婴阻断前的母婴传播途径感染比例为0.77%(2/260),其母婴自然传播率为28.6%(2/7);2004年7月实施母婴阻断后未发现经母婴传播的婴幼儿。结论随州市HIV的感染人群已由高危人群向普通人群转换,孕产妇人群中艾滋病的感染问题日趋严重,应引起高度重视;对孕妇提供AIDS自愿咨询检测服务和对HIV孕产妇采取综合性干预措施,可有效防止或阻断HIV母婴垂直传播的发生。Objective To know the situation of the HIV-positive mother to infant transmission in Suizhou,to explore the approaches of preventing or blocking mother-to-infant transmission of HIV,and to provide the evidence for prevention and control of vertical transmission of HIV.Methods HIV-positive pregnant women who took part in voluntary counseling and their infants in Suizhou from 2002 to 2008 were selected,and a comprehensive intervention was conduct on the HIV-positive pregnant women and their infants who were detected after July,2004.Results Totally 15 HIV-positive pregnant women and 2 HIV-positive infants were found in Suizhou during the period of 2002～2008.The infection ratio of HIV-positive mother to infant transmission was 0.34%（2/591） and the natural spread rate was 13.33%（2/15）.Before the intercepting mother-to-infant transmission,the infection ratio of mother to infant transmission was 0.77%（2/260） and the natural spread rate of mother to infant was 28.6%（2/7）.No HIV-positive infant who was transmitted by his mother was found after July,2004.Conclusions Maternal HIV infection becomes more and more serious in Suizhou,so attention should be paid to preventing or blocking mother-to-infant transmission of HIV.These approaches,such as providing AIDS voluntary counseling for pregnant women and conducting integrated interventions on pregnant women,can effectively prevent or block the vertical transmission.

关 键 词：阻断 艾滋病 母婴传播 效果 

分 类 号：R512.91[医药卫生—内科学]