脊髓灰质炎后综合征的临床与电生理特点(附2例报告)  

Clinical and Electrophysiological Features of Post-poliomyelitis Syndrome:a Report of Two Cases

作　　者：牛琦[1] 万琪[1] 王红星[2] 

机构地区：[1]南京医科大学第一附属医院神经科,江苏南京210029 [2]南京医科大学第一附属医院康复科

出　　处：《实用预防医学》2010年第10期2019-2020,共2页Practical Preventive Medicine

基　　金：江苏省自然科学基金项目(BK2007607)

摘　　要：目的研究2例脊髓灰质炎后综合征(PPS)的临床表现和电生理特点。方法对2例脊髓灰质炎患者临床和肌电图进行回顾性分析。结果病例1,男性,61岁,在脊髓灰质炎后39年发病,表现为右下肢(原患肢)重新出现肌肉无力,肌萎缩和肌束颤动,并逐渐波及对侧和双上肢。肌电图出现患肢慢性失神经的改变,一年后随访肌电图,病变进展至胸段和上肢肌。患者2,女性,在脊髓灰质炎后45年发病,双下肢出现肌肉无力和萎缩,以原患者肢为著,肌电图示双下肢慢性失神经表现。结论 PPS是脊髓灰质炎多年以后重新出现的慢性运动神经元的损害,肌电图随访有助于帮助判断病情进展情况。Objective To study the clinical and electrophysiological characteristics of two cases of post-poliomyelitis syndrome（PPS）.Method Clinical data of two patients with PPS were retrospectively analyzed.Results Patient 1,male,61 years old,he represented new weakness and atrophy from his affected limb to contralateral limb and both upper limbs gradually after suffering from poliomyelitis 39 years.Electromyography（EMG） showed the signs of denervation in affected extremity.The following-up EMG demonstrated that the lesion involved in truncal and upper limb muscles.Patient 2,female,she represented new weakness and atrophy in both lower limbs after suffering from poliomyelitis 45 years. Both lower limbs showed the signs of denervation in electromyography.Conclusions PPS is a newly and slowly progressive motor neuron injury after many years of poliomyelitis.EMG is useful to monitoring the progress of the disease.

关 键 词：脊髓灰质炎后综合征 临床表现 电生理特点 

分 类 号：R512.4[医药卫生—内科学]