精元康胶囊对不同治疗方案的116例HIV/AIDS患者白细胞水平影响的随机对照研究  

Randomized Double-blind Trials of Jingyuankang Capsule on Peripheral Blood Leukocyte in HIV/AIDS Cases

作　　者：蒋士卿[1] 孙宏新[2] 徐英敏[1] 裴俊文[3] 王红玲[1] 

机构地区：[1]河南中医学院,郑州450008 [2]河南省中医院,郑州450002 [3]河南省肿瘤医院,郑州450008

出　　处：《中国实验方剂学杂志》2010年第14期201-203,206,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技部"十五"科技攻关计划(2004BA719A09-0203)

摘　　要：目的:观察精元康胶囊对艾滋病外周血象低下的治疗效果。方法:选用中药制剂精元康胶囊+利可君片模拟剂与HAART疗法同时服用组患者58例,并与西药利可君片+精元康胶囊模拟剂与HAART疗法同时服用患者58例,采用随机、双盲、双模拟剂的临床试验方法,均系统服药6个月,定期检测患者外周血象,以观察精元康胶囊对艾滋病不同程度的白细胞低下的治疗效果。结果:精元康胶囊治疗艾滋病外周血象低下效果良好,服用含齐多夫定(AZT)HAART方案的患者与服用不含齐多夫定(AZT)的HAART方案者比较,均显示出提升白细胞作用。精元康胶囊临床安全有效,治疗中及后期随访均未观察到本制剂引起的毒副作用和不良反应。结论:精元康胶囊可有效治疗艾滋病患者外周血象低下。Objective：To observe the the therapeutic effect on peripheral blood leukocyte reduction of AIDS by Jingyuankang Capsule.Method：116 cases of HIV /AIDS patients were divided into two groups：58 cases in the treatment were treated by Jingyuankang Capsule and likejun mimic tablet with HAART therapy,and the other 58 cases in the control by likejun tablet and mimic Jingyuankang Capsules with HAART.The design was a randomized double-blind research,and 6 months as a course.Peripheral blood leukocytes were monitored for these cases.Result：Jingyuankang Capsule treatment for AIDS showed good effect,whether they had taken with AZT（HAART） or not.HAART scheme showed that it could improve peripheral blood leukocytes.Jingyuankang Capsule appeared safe and effective.Through clinical investigation and follow-up the capsule showed no toxicity and adverse reaction.Conclusion：Jingyuankang Capsules can effectively treat AIDS patients with reduction in peripheral blood leukocyte.

关 键 词：HIV/AIDS 中医药治疗 随机对照 双盲法 双模拟 临床研究 

分 类 号：R285.6[医药卫生—中药学]