自拟中药与胸腺肽对扁平疣患者细胞免疫功能影响的比较  

Contrastive observation of the effects between the pinyou fangji and thymopeptide on T-lymphocyte subpopulation in patients with Verruca plana

作　　者：郗宁[1] 郝江华[2] 

机构地区：[1]甘肃省人民医院检验科,兰州730000 [2]甘肃省人民医院皮肤科,兰州730000

出　　处：《国际检验医学杂志》2010年第10期1072-1072,1075,共2页International Journal of Laboratory Medicine

摘　　要：目的对比研究自拟中药"平疣方剂"与胸腺肽治疗扁平疣患者T细胞亚群的变化。方法将120例扁平疣患者随机分为2组,分别给予"平疣方剂"和"胸腺肽胶囊"服用,采用AP-AAP法检测2组患者用药前、后外周血T淋巴细胞亚群,以评价"平疣方剂"对扁平疣患者细胞免疫功能的影响。结果 "平疣方剂"与"胸腺肽胶囊"均能提高扁平疣患者外周血CD4+T淋巴细胞百分比及CD4+/CD8+比值,且"平疣方剂"效果显著优于"胸腺肽胶囊"(P<0.01)。结论自拟"平疣方剂"可以提高扁平疣患者细胞免疫功能。Objective To observe the effect of the pinyou fangji and thymus peptide on the T-lymphocyte subpopulation in patients with Verruca plana and the effect of treatment. Methods 120 patients with Verruca plana were divided randomly into two groups：The patients were treated with the pinyou fangji, compared with thymus peptide treatment. We examined T lymphocyte subsets by APAAP before treatment and after treatment. Results The pinyou fangji and Thymus peptide can improve the percentages of CD4^＋ Tlymphocytes and the CD4^＋/CD8^＋ ratio,and the pinyou fangji was significantly higher than thymus peptide（P〈 0.01）. Conclusion The pinyou fangji can significantly improve the cell immunity function of patients with Verruca plana.

关 键 词：中药疗法 胸腺 肽类 疣 T淋巴细胞亚群 

分 类 号：R752.5[医药卫生—皮肤病学与性病学]