健康体检中血清胆红素升高的相关因素分析及建议  

Factors related to elevated bilirubin in Physical Examination and suggestions

作　　者：王升声[1] 盖小荣[1] 楼慧萍[1] 莎仁高娃[1] 孙杰[1] 王建[1] 

机构地区：[1]中国医学科学院北京协和医院健康医学部,北京100032

出　　处：《中国实验诊断学》2010年第10期1626-1627,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的分析健康体检中血胆红素升高的相关因素,并提出建议。方法统计11 697份健康体检资料,其中血清胆红素升高718例,分析其与年龄、体重指数、血脂、肝功能、肾功能的相关性。结果血清胆红素升高发生率6.1%;胆红素升高组与对照组作相关性的t检验,提示胆红素升高与年龄、体重指数、总胆固醇、甘油三酯、低密度脂蛋白、乳酸脱氢酶呈负相关,与血尿素氮、肌酐呈正相关,结果具有统计学意义(P<0.05)。结论健康人的血清胆红素轻度升高有利于减少个体发生冠心病的可能;建议按照不同年龄段调整血清胆红素参照值的上限。Objective To investigate the related factors of elevated bilirubin in physical examination groups and to give suggestions.Methods 11 697 cases of physical Examination were reviwed,among which 718 cases were bilirubin elevating.The relationship of elevated bilirubin with age,BMI and Blood biochemistry,etc were analyzed.Results The ratio of bilirubin elevating is 6.1% in routine physical Examination groups.There were significant differences in BMI,CHO,TCH,LDL,LD,BUN and CR between the bilirubin elevating group and the control group.While BMI,CHO,TCH,LDL,LD were negatively correlated with elevated bilirubin;and BUN CR were conversely correlated respectively P0.05.Conclusion Bilirubin elevating in healthy groups trends to reduce the risks of coronary heart disease.Therefore the upper limit of the reference value in bilirubin is suggested to be up-scaled.

关 键 词：健康体检 胆红素 冠状动脉疾病 年龄 参照值 

分 类 号：R194.3[医药卫生—卫生事业管理]