益气化瘀利水方治疗膝骨关节炎的临床疗效观察  

Clinical curative effects of Yiqi-Huayu-Lishui prescription on knee osteoarthritis

作　　者：高翔 吴弢 瞿佶 苟海昕 李蠡 张霆[2] 莫文[2] 吴耀持[3] 唐德志[4] 

机构地区：[1]复旦大学附属华东医院伤外科,上海市200040 [2]上海中医药大学附属龙华医院骨伤科,上海市200032 [3]上海交通大学附属第六人民医院针推伤科,上海市200233 [4]上海中医药大学脊柱病研究所,上海市200032

出　　处：《老年医学与保健》2010年第5期315-317,共3页Geriatrics & Health Care

基　　金：基金项目：上海市申康医疗发展中心中医验方项目科研基金课题（编号：SHDC2008411）

摘　　要：目的评价益气化瘀利水方治疗膝骨关节炎的临床疗效。方法采用随机对照单盲试验方法，参照GoldbergVM及LegnesneMG的膝骨关节炎临床评估指数打分表评价了益气化瘀利水方与塞来昔布（西乐葆）治疗100例膝骨关节炎的临床疗效。结果两组病例基线可比，治疗后1个月随访时，益气化瘀利水方组的积分与西乐葆组相似。结论益气化瘀利水方对膝骨关节炎的治疗效果与西乐葆相似，但其经济性更为突出，安全性更佳。Objective To evaluate the clinical curative effects of Yiqi-Huayu-Lishui prescription on knee osteoarthritis. Methods Using a randomized controlled single blinded clinical trial, 100 patients were randomly divided into two group： experimental group （n=50） treated with Yiqi-Huayu-Lishui prescription for 4 weeks and comrol group （n =50） treated with Celebrex for 4 weeks via oral. Goldberg VM and Legnesne MG Score Charts were used to evaluate the curative effects. Results There were no significant difference in the scores between the two groups. Conclusion Yiqi-Huayu-Lishui prescription and Celecoxib have the same curative effect on osteoarthritis, while the former is cheaper and safer.

关 键 词：益气化瘀利水方 膝骨关节炎 随机对照单盲试验 

分 类 号：R285[医药卫生—中药学]