土牛膝提取物对正常及四氧嘧啶糖尿病模型小鼠血糖的影响  

作　　者：马文杰[1,2] 魏得良[3] 黄志芳 黄志红[3] 胡吉林[3] 刘大鹏[3] 

机构地区：[1]湘南学院附一医院 [2]郴州市第一人民医院,423000 [3]湘南学院化学与生命科学系 [4]广州市第十三人民医院,510620

出　　处：《当代医学》2010年第30期4-5,共2页Contemporary Medicine

基　　金：湖南省教育厅科研基金资助项目(05C630);湖南省科技厅科研基金资助项目(06FJ4099)

摘　　要：目的研究土牛膝提取物齐墩果酸、牛膝多糖对正常及四氧嘧啶糖尿病模型小鼠血糖的影响。方法采用正常小鼠和四氧嘧啶糖尿病模型小鼠,用邻甲苯胺法测定血糖值。结果土牛膝提取物齐墩果酸、牛膝多糖对正常小鼠空腹血糖无明显降低作用,能明显降低四氧嘧啶糖尿病模型小鼠的空腹血糖水平。结论土牛膝提取物齐墩果酸、牛膝多糖对糖尿病模型小鼠有较好的降糖作用。Objective To study the effects of extra of local achyranthes aspera,oleanolic acid（OA） and achyranthes bidentata polysaccharides（ABPS）,on normal and alloxan diabetic mice. Methods Normal and alloxan diabetic mice are used. Determining their blood glucose by means of o-Toluidine method （O-T）.Results OA and ABPS have obvious effects on lowering the blood glucose in alloxan induced diabetic model mice,while have no obvious effecs on normal limosis mice. Conclusion OA and ABPS which are extracted from local achyranthes aspera have quite obvious fuctions in the diabetic mice treatment.

关 键 词：土牛膝 齐墩果酸 牛膝多糖 四氧嘧啶 血糖 

分 类 号：R285.5[医药卫生—中药学]