药物多晶型现象研究进展  

Research Advance of Drug Polymorphism

作　　者：周肖寅[1] 刘峥[1] 冯小珍 

机构地区：[1]桂林理工大学化学与生物工程学院,广西桂林541004 [2]桂林南药股份有限公司,广西桂林541004

出　　处：《化学与生物工程》2010年第10期1-5,共5页Chemistry & Bioengineering

摘　　要：药物多晶型自发现以来受到了广泛关注,多晶型的研究取得了巨大成就,但药物种类繁多,新药不断出现,多晶型的研究任务依然艰巨。通过对近10年来国内外药物多晶型研究相关文献的整理、分析与归纳,介绍了药物多晶型现象的研究意义、分析方法、多晶型转变的影响因素。Drug polymorphism has received extensive attention since it had been discovered,and scientists have got great achievements in research of polymorphism.However,the drug variety is so large and with the invention of new drugs,the research of polymorphism is also an arduous task.In this paper,on the basis of research,analysis and summary of a near decade of correlative literatures,the drug polymorphism,the research significance,the analysis method,the influential factors of crystal transformation.

关 键 词：药物多晶型 分析方法 晶型转变 

分 类 号：O742.4[理学—晶体学]