应变率成像评价2型糖尿病患者左室舒张功能  

Evaluation of left ventricular diastolic function in patients with type 2 diabetes mellitus by strain rate imaging

作　　者：吴田[1] 郭瑞强[1] 陈金玲[1] 

机构地区：[1]武汉大学人民医院超声影像科,武汉430060

出　　处：《临床心血管病杂志》2010年第10期740-742,共3页Journal of Clinical Cardiology

摘　　要：目的:探讨应变率成像技术早期诊断2型糖尿病患者左室舒张功能异常的临床价值。方法:2型糖尿病患者和正常对照者各25例,获取心尖四腔、心尖两腔、心尖左室长轴观心肌应变率曲线,测量左室各节段舒张早期和舒张晚期纵向峰值应变率,并计算基底段、中间段、心尖段舒张早期平均峰值应变率(SRe)和舒张晚期平均峰值应变率(SRa)及SRe/SRa比值。结果:与对照组比较,2型糖尿病患者SRe和SRe/SRa减低,各节段差异均有统计学意义(P<0.05,0.01),SRa差异无统计学意义。结论:应变率成像技术能够早期评价2型糖尿病患者左室舒张功能的异常,并为临床提供一定的信息。Objective：To assess the value of strain rate imaging in detecting left ventricular diastolic function in patients with type 2 diabetes mellitus.Method：Twenty-five patients with type 2 diabetes mellitus（T2DM）and 25 normal controls were studied.Tissue velocity imaging of all patients and controls were accepted in apical two,four and long axis chamber views.Strain rate（SR）imaging was performed on all subjects.Peak SR was measured at each segment of left ventricle during early diastole and atrial contraction,mean peak early diastolic SR（SRe）and mean peak atrial systolic SR（SRa）in the long axis at basal,middle and apical levels were assessed,as well as the ratio of SRe/SRa.Result：Compared with the controls,SRe of different segments in patients with T2DM and the ratio of SRe/SRa were significantly reduced（P0.05,0.01）,while SRa had no significant difference.Conclusion：SR imaging would be a new and accurate method to evaluate left ventricular diastolic function in patients with T2DM,which may take some clinical information.

关 键 词：糖尿病 超声心动描记术 应变率成像 左室 舒张功能 

分 类 号：R587.1[医药卫生—内分泌]