非肌层浸润膀胱移形上皮癌二次电切术疗效分析及意义(附42例报告)  

Clinical effects and significance of second turbt in superficial transitional cell carcinoma of the bladder

作　　者：霍庆祥[1] 孙建涛[1] 张寒[1] 张艺[1] 

机构地区：[1]河南省洛阳市中心医院泌尿外科,河南洛阳471000

出　　处：《中国内镜杂志》2010年第9期953-955,共3页China Journal of Endoscopy

摘　　要：目的探讨经尿道非肌层浸润膀胱移形上皮癌二次电切术的疗效和意义。方法非肌层浸润膀胱移形上皮癌42例,经尿道电切术后4～6周再次电切,术后标本病理组织学评估,评价肿瘤复发和进展情况。结果二次电切术中33.3%有残余肿瘤。残余肿瘤与原发肿瘤大小(直径>3cm)、数目(≥3个)、高分级相关。平均随访12个月,11.9%复发,二次电切时残余肿瘤与复发相关。结论多发、直径>3cm及高分级者与二次电切中肿瘤残余有关;肿瘤直径>3cm、残余与肿瘤复发明显相关。【Objective】To explore the clinical effects of second TURBT in superficial transitional cell carcinoma of the bladder.【Methods】42 patients with superficial bladder cancer underwent second TURBT after 4 to 6 weeks of initial TURBT and histological evaluation of these specimens.Patients were followed-up,tumor recurrence and progression rates were compared.【Results】Residual tumors were found in 33.3%（14/42） patients underwent second TURBT.Residual tumors had a statistically significant correlation with size of the tumor（3 cm）,number（≥3） and grade（high）.In follow-up of mean 12 months,11.9% had recurrence.Presence of residual growth in second TURBT have significant correlation with the recurrence.【Conclusions】Multiple,more than 3 cm,previous resections were predictors of presence of residual tumor in second TURBT.Presence of residual growth and more than 3 cm is a significant risk factor for recurrence.

关 键 词：膀胱 移形上皮癌 二次电切 

分 类 号：R694[医药卫生—泌尿科学]