正常胰腺及胰腺占位病变超声内镜弹性成像特点初步研究  

EUS elastographic patterns of normal pancreas and focal pancreatic lesions

作　　者：徐凯[1] 任大宾[1] 孙晓敏[1] 王静[1] 徐萍[1] 

机构地区：[1]上海交通大学附属上海市第一人民医院松江分院消化内科,201600

出　　处：《中华消化内镜杂志》2010年第9期461-464,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的 初步探讨正常胰腺及胰腺与位病变的超声内镜弹性成像特征及其在良恶性鉴别中的价值.方法 自2009年1月至6月,对9例胰腺占位病变行EUS的患者同时进行超声内镜实时弹性成像,同时选取6例因其他病变而行EUS者的正常胰腺行超声内镜实时弹性成像作对照,按照弹性成像5分法对组织弹性成像进行评分.结果 9例胰腺占位病变患者最终诊断为胰腺癌4例,囊腺癌1例,囊腺瘤2例,局限性胰腺炎2例,其弹性成像评分：胰腺癌1例3分、3例4分,囊腺癌5分,2例囊腺瘤均为2分,局限性胰腺炎2分和3分各1例;6例正常胰腺者其弹性成像评分1分5例,2分1例.当以1、2分为良性,3～5分为恶性病变的标准进行判断时,超声内镜弹性成像对9例胰腺占位性病变良恶性鉴别有8例准确.结论 胰腺良恶性组织弹性成像呈不同的图像特征,超声内镜实时弹性成像有助于胰腺良恶性病变的鉴别.Objective To investigate the EUS elastographic patterns of normal pancreas and focal pancreatic lesions, and its value for characterizing and differentiating between benign and malignant pancreatic tissues. Methods Between January and June 2009, 6 patients with normal pancreas and 9 patients with focal pancreatic lesions were enrolled. Real-time elastography was carried out during the conventional EUS examination. The elastographic images were scored with 1 to 5 based on the elastographic pattern. Results Nine focal pancreatic lesions were finally diagnosed as pancreatic cancer （n = 4）, cyst-adenocarcinoma （n =1）, cyst-adenoma （n = 2） and focal pancreatitis （n = 2）, respectively. Pancreatic cancers were scored as 3（n = 1） and 4 （n = 3）. Cyst-adenocarcinoma was scored as 5 and cyst-adenomas were scored both as 2,while focal pancreatitis were scored as 2 and 3, respectively. Elastographic pattern was scored as 1 （n = 5）and 2 （n = 1） in 6 normal pancreas. When scores 1 and 2 were assigned to benign lesion and 3 to 5 to malignancy, the overall diagnostic accuracy of EUS elastography for focal pancreatic lesions was 88. 9%（8/9）. Conclusion There are apparent differences in elastographic patterns between benign and malignant pancreatic tissues. EUS elastography is a promising method that allows characterization and differentiation of benignancy and malignancy.

关 键 词：胰腺 内窥镜超声检查 弹性成像 诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学]