女性腰椎投影骨面积对骨密度及骨质疏松诊断的影响  

Effects of projective bone area of lumbar spine on bone mineral density and diagnosis of osteoporosis in women

作　　者：黄际远[1] 宋文忠[1] 史克俭[1] 黄劲[1] 钟兴华[1] 

机构地区：[1]四川省人民医院核医学科,成都610072

出　　处：《中国骨质疏松杂志》2010年第10期730-732,共3页Chinese Journal of Osteoporosis

摘　　要：目的观察健康女性腰椎投影骨面积(projective bone area,BA)对面积骨密度(areal bonemineral density,aBMD)和骨质疏松(osteoporosis,OP)诊断的影响。方法 1.成都地区健康女性824例,年龄20～80岁,用GE LUNAR公司生产的EXPERT-XL双能X线骨密度仪,测定腰椎正位1-4投射骨面积(BA)、骨矿物含量(bone mineral content,BMC)、面积骨密度(aBMD)。按照WHO推荐的诊断标准:aBMD低于峰值骨2.5个标准差为OP。2.按年龄分为20～39岁、40～59岁、60～80岁3个年龄组。各年龄组按BA大小分成大(large BA group,LBAG)、中(intermediate BA group,IBAG)、小(small BA group,SBAG)3组。3.统计学处理:用SPSS13.0统计软件,BA与BMC和aBMD的相关性用pearson相关分析;不同年龄组不同BA组腰椎BMC、aBMD比较用方差分析,OP检出率差异比较用卡方检验。结果 1.BA与BMC(r=0.768P<0.01)和aBMD呈正相关(r=0.171P<0.01);2.20～39岁、40～59岁、60～80岁不同BA组BMC、BMD比较均为:LBAG>IBAG>SBAG,差异有统计学意义(P<0.05)。3.20～39岁不同BA组均无OP检出;40～59岁LBAG、IBAG、SBAG组OP检出率分别为:5.0%、13.5%、18.9%,BA越大,OP检出率越低,差异有统计学意义(P<0.05);60～80岁LBAG、IBAG、SBAG组OP检出率分别为:45.2%、55.8%、64.3%,BA越大,OP检出率越低,差异有统计学意义(P<0.05)。结论成都地区健康女性腰椎BA大者aBMD、BMC较高,OP检出率较低;反之腰椎BA小者,aBMD、BMC较低,OP检出率高。女性40岁后应注意骨质疏松防治。Objective To investigate the effects of projective bone area （BA） of lumbar spine on area bone mineral density （aBMD） and diagnosis of osteoporosis （OP） in healthy women. Methods 1 ） BA, bone mineral content （BMC）, and aBMD of lumbar spine L1-4 of 824 healthy women in Chengdu, aged 20-80 years old, were measured using dual energy X-ray absorptiometry （ Lunar Expert-XL）. According to the diagnosis criteria recommended by WHO, OP was diagnosed when aBMD was lower than 2. 5 standard deviation of peak bone mass. 2） Three groups were divided according to the age： 20-39 years old group, 40- 59 years old group, and 60-80 years old group. Each group was sub-divided into three subgroups according to BA： large BA （LBAG） , intermediate BA （IBAG） , and small BA group （SBAG）. 3） The results were analyzed using SPSS 13.0 software. The correlations of BA, BMC, and aBMD were analyzed by Pearson method. The comparison of BMC and aBMD between different age groups and different BA subgroups were analyzed by one-way analysis of variance. The difference compares of detection rate of OP were analyzed by Chi square test. Results 1 ） Significant positive correlations between BA and BMC （ r = 0. 768, P 〈 0.01 ） and between BA and aBMD （ r = 0. 171 ,P 〈 0. 01 ） were found. ：2 ） The comparison of BMC and BMD among the different BA subgroup of each age group showed that LBAG 〉 IBAG 〉 SBAG （P 〈 0.05） and the difference was statistically significant. 3） The OP detection rate in different BA subgroups of 20-39 years old group was none. The OP detection rates of LBAG, IBAG, and SBAG in 40-59 years old group were 5.0% , 13.5%, and 18.9%, respectively. Following BA increasing, the OP detection rate decreased. The difference was statistically significant （P 〈 O. 05 ）. The OP detection rates of LBAG, IBAG, and SBAG in 60-80 years old group were 45.2% , 55.8% , and 64.3% , respectively. Following BA increasing, the OP detection rate decreased. The difference was statistica

关 键 词：腰椎 投影骨面积 面积骨密度 骨质疏松 

分 类 号：R181.37[医药卫生—流行病学]