中药射干的化学成分分析  

Studies on chemical constituents of Belamcanda chinensis

作　　者：冯传卫[1] 沈刚[1] 陈海生[1] 

机构地区：[1]第二军医大学药学院天然药物化学教研室,上海200433

出　　处：《第二军医大学学报》2010年第10期1120-1122,共3页Academic Journal of Second Military Medical University

基　　金：上海市科委登山计划(7dZ19721-2);上海市重点实验室建设资助(B906)~~

摘　　要：目的对中药射干Belamcanda chinensis(L.)DC根茎80%乙醇提取物进行化学成分分析。方法利用硅胶色谱、Sephadex LH-20色谱以及反相HPLC等手段进行分离纯化,应用MS、NMR等光谱方法对分得的化合物进行结构鉴定。结果从射干根茎中分离并鉴定了10个化合物,分别为鸢尾苷(tectoridin,Ⅰ),香草乙酮(acetovanillone,Ⅱ),对羟基苯乙酮(4-hydroxy-acetophenone,Ⅲ),β-谷甾醇(β-sitosterol,Ⅳ),β-胡萝卜苷(β-daucosterol,Ⅴ),5,7,4′-三羟基-3′,5′-二甲氧基黄酮(5,7,4′-trihydroxyl-3′,5′-dimethoxyflavone,Ⅵ),木犀草素(luteolin,Ⅶ),芹菜素(apigenin,Ⅷ),5,7,4′-三羟基二氢黄酮(5,7,4′-trihydroxyflavanones,Ⅸ),异鼠李素(isorhamnetin,Ⅹ)。结论化合物Ⅵ、Ⅶ、Ⅷ、Ⅸ为首次从射干中分离得到。Objective To investigate the chemical constituents of 80% ETOH extract from rhizome of Belamcanda chinensis（L.）DC.Methods The constituents were isolated and purified by chromatography on silica gel,Sephadex LH-20 and HPLC;the structures of the compounds were determined by MS and NMR spectral analysis.Results Ten constituents were identified from rhizome of Belamcanda chinensis（L.）DC,including tectoridin（Ⅰ）,acetovanillone（Ⅱ）,4-hydroxy-acetophenone（Ⅲ）,β-sitosterol（Ⅳ）,β-daucosterol（Ⅴ）,5,7,4′-trihydroxyl-3′,5′-dimethoxyflavone（Ⅵ）,luteolin （Ⅶ）,apigenin（Ⅷ）,5,7,4′-trihydroxyflavanones（Ⅸ）,and isorhamnetin（Ⅹ）.Conclusion CompoundsⅥ,Ⅶ,Ⅷ,andⅨ have been isolated from rhizome of Belamcanda chinensis for the first time.

关 键 词：射干 化学成分 黄酮类 

分 类 号：R284.1[医药卫生—中药学]