应用N-乙酰-L-半胱氨酸合成紫色-近红外荧光发射的量子点  

Synthesis of violet-near-infrared-emitting quantum dots using N-acetyl-L-cysteine as ligand

作　　者：薛冰[1] 邓大伟[1] 曹洁[1] 郭静[1] 张俊[1] 顾月清[1] 

机构地区：[1]中国药科大学生命科学与技术学院生物医学工程教研室,南京210009

出　　处：《中国药科大学学报》2010年第5期456-461,共6页Journal of China Pharmaceutical University

基　　金：国家自然科学基金资助项目(No.30800257;No.30700779;No.30970776)~~

摘　　要：应用生物活性分子N-乙酰-L-半胱氨酸（NAC）作为配体,采用加热回流和水热合成法制备具有紫色-近红外荧光发射、高质量的水溶性碲化镉量子点（CdTe QD s）,并通过紫外可见、荧光分光光度计表征量子点的光学性质,透射电镜（TEM）和粉末X射线衍射（XRD）表征量子点结构。结果表明,以N-乙酰-L-半胱氨酸为配体可以合成出荧光量子产率为11%-62.4%、荧光发射峰在415-800 nm宽范围内可调的Zn1-xCdxSe和CdTe水溶性量子点。XRD结果表明量子点荧光发射峰与其粒径相关。这是首次应用单一配体——N-乙酰-L-半胱氨酸作为稳定剂,合成具有紫色近红外宽荧光发射的水溶性荧光量子点。用此方法制备的水溶性量子点具有较好的荧光量子产率、较窄的半峰宽以及较强的光稳定性。Facile refluxing or hydrothermal methods were used and bioactive molecule N-acetyl-L-cysteine（NAC） was employed as the ligand to synthesize water-soluble CdTe quantum dots（CdTe QDs） with strong and widely tunable fluorescence emission.Their optical properties were measured with UV-vis spectrophotometer and spectrofluorometer.In addition,the morphology and structure of QDs were further characterized by TEM and XRD.By using NAC as the stabilizer,high-quality aqueous Zn1-xCdxSe and CdTe QDs were successfully synthesized with the quantum yields（QYs） reach of up to 62.4%.XRD analysis indicated that the fluorescent emission peaks of QDs were related to their sizes.Using NAC as the ligand,the resulting water-soluble quantum dots were highly fluorescent with the novel property that their fluorescent emission peaks were tunable from 415 nm to 800 nm,i.e.,in the violet-near-infrared（spectral range.The as-prepared QDs exhibited high photoluminescence quantum yields,narrow full-width at half-maximum and high photostability.

关 键 词：水溶性量子点 N-乙酰-L-半胱氨酸 紫色-近红外荧光发射 Zn1-xCdxSe量子点 CDTE量子点 

分 类 号：O649[理学—物理化学]