ICUS图像序列中冠状动脉的三维重建和形态测量  

3D Reconstruction and Morphological Measurement of Coronary Artery from Intracoronary Ultrasound Image Sequence

作　　者：孙正[1] 韩少勤[1] 

机构地区：[1]华北电力大学电子与通信工程系,保定071003

出　　处：《中国生物医学工程学报》2010年第5期688-696,共9页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(30500129;60973087);华北电力大学"211工程"三期校内面上项目

摘　　要：针对冠状动脉内超声(ICUS)图像序列中血管的三维重建问题,提出一种从连续回撤超声导管获取的、覆盖多个心动周期的ICUS序列中准确重建冠脉血管、并定量测量其形态结构参数的方法。首先利用在导管回撤路径起点采集的两幅近似垂直的X射线冠脉造影(CAG)图像之间的交叉信息,重建出导管的回撤路径,然后从各帧ICUS图像中提取出血管壁的内外轮廓;在对ICUS序列中由心脏运动所致的运动伪影进行补偿之后,选择出在各心动周期的同一时相处采集的ICUS帧,并将其沿三维导管路径顺序排列;最后采用NURBS曲面拟合技术,完成血管的三维重建。根据该三维血管模型,对临床重要的血管形态参数进行测量,采用临床图像数据进行验证。实验结果证明,较之仅采用CAG图像或ICUS序列重建出的血管模型的测量结果,该方法更为精确。An approach for reconstructing and quantitatively measuring coronary arterial morphology from continuous pullback intracoronary ultrasound（ICUS） image sequence covering several cardiac cycles was proposed in this paper.Firstly,the pullback trajectory of the ultrasonic imaging catheter was reconstructed based on the volumetric information of two nearly orthogonal X-ray coronary angiographic（CAG） projections acquired at the origin of the pullback path.Then,vessel wall boundaries were detected from each ICUS frame.Once motion artifacts due to cardiac motion existing in the ICUS sequence were compensated,those ICUS frames acquired at the same phase of successive cardiac cycles were selected and correctly aligned along the pullback path in the acquisition order.Finally,the vessel was accurately reconstructed with the NURBS surface fitting technique.Clinically important morphological parameters were quantitatively measured with the reconstructed vessel model.Experimental results with clinical image data demonstrated that the measurement results with the proposed method were more accurate than those with the 3D vessel model reconstructed from only CAG or ICUS sequence.

关 键 词：冠状动脉内超声 X射线冠状动脉造影 三维重建 测量 形态参数 

分 类 号：TP391[自动化与计算机技术—计算机应用技术] R816.2[自动化与计算机技术—计算机科学与技术]