舒芬太尼复合罗哌卡因应用于妊娠期糖尿病分娩镇痛的临床研究  

Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus

作　　者：吴玲玲[1] 范建辉[1] 尹玉竹[1] 王林琳[1] 朱娟[1] 侯红瑛[1] 

机构地区：[1]中山大学附属第三医院妇产科

出　　处：《中国临床药理学与治疗学》2010年第8期920-923,共4页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：广东省科技计划项目资助(2007B031501007)

摘　　要：目的:探讨舒芬太尼复合罗哌卡因应用于分娩镇痛对妊娠期糖尿病(gestational diabetes mellitus,GDM)分娩结局及产程中血糖水平的影响。方法:125例GDM产妇,采用舒芬太尼复合罗哌卡因实施腰麻-硬膜外联合(combined spinal-epidural,CSE)分娩镇痛的60例为研究组,未选择分娩镇痛的65例为对照组,评定舒芬太尼复合罗哌卡因的镇痛效果并比较两组产妇的分娩结局及血糖水平。结果:研究组于麻醉成功后10min内均达到镇痛效果;研究组第一产程活跃期时限长于对照组(P<0.05),产程中剖宫产率低于对照组(P<0.05),产程中血糖水平低于对照组(P<0.05)。结论:舒芬太尼复合罗哌卡因应用于GDM的分娩镇痛效果确切,有益于产程中血糖水平的稳定,降低剖宫产率。AIM：To evaluate the effect of sufentanil combined ropivacaine for labor anesthesia on labor outcome and blood glucose during childbirth of gestational diabetes mellitus.METHODS：125 cases of gestational diabetes mellitus who selected vaginal delivery,60 cases in study group received sufentanil combined ropivacaine for pain relief during childbirth,65 cases in control group without any pain relief during childbirth,labor outcome and blood glucose during childbirth were compared between two groups.RESULTS：Patients in study group felt pain relief in ten minutes since receiving CSEA.The duration of active phase in the first stage in study group was significantly longer than that of control group（P0.05）.Patients who received cesarean section（CS）in study group were lower than that of control group（P0.05）.Blood glucose during childbirth was significantly lower in study group than that of control group（P 0.05）.CONCLUSION：Sufentanil combined ropivacaine could alleviate labor pain,stabilize blood glucose and reduce CS rate during childbirth in GDM patients.

关 键 词：舒芬太尼 罗哌卡因 分娩镇痛 妊娠期糖尿病 分娩结局 血糖 

分 类 号：R614[医药卫生—麻醉学]