早期血液净化治疗横纹肌溶解症的临床效果  

Clinic study on early blood purification in treatment of rhabdomyolysis

作　　者：陈椰[1] 王海涛[1] 张虹[1] 童俊容[1] 张建林[1] 

机构地区：[1]广州军区广州总医院肾脏内科,广东广州510010

出　　处：《现代医学》2010年第5期498-500,共3页Modern Medical Journal

摘　　要：目的:观察早期血液净化治疗对横纹肌溶解症的临床效果。方法:32例横纹肌溶解症患者于起病后72 h内接受血液净化治疗,监测治疗前后患者血肌红蛋白、肌酸磷酸激酶(CPK)、肌酸磷酸激酶同工酶(CPK-MB)、血肌酐(Cr)、血尿素氮(BUN)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)水平,并观察预后。结果:治疗后患者的血肌红蛋白、CPK、CPK-MB、Cr、BUN、AST、ALT、LDH均明显低于治疗前;31例患者痊愈,1例死于脑梗死。结论:早期血液净化治疗对于救治横纹肌溶解患者有良好的疗效。Objective： To investigate the effect of early blood purification in the treatment of rhabdomyolysis.Methods： Thirty-two patients with rhabdomyolysis were taken blood purification in 72 hours after they got the disease.Serum concentration of myohemoglobin,creatine phosphokinase（CPK）,creatine phosphokinase-isoenzyme-MB（CPK-MB）,creatinine（Cr）,urea nitrogen（BUN）,alanine aminotransferase（ALT）,aspartate aminotransferase（AST） and lactate dehydrogenase（LDH） were measured before and after the treatment.Results： After the treatment,the average serum levels of myohemoglobin,CPK,CPK-MB,Cr,BUN,AST,ALT,LDH were significantly decreased.Thirty-one cases recovered,1 patient died for cerebral infarction.Conclusions： Early blood purification is effective in treating rhabdomyolysis.

关 键 词：横纹肌溶解症 血液净化 早期 

分 类 号：R459.5[医药卫生—治疗学]