新型花状纳米四氧化三钴修饰玻碳电极对芦丁的电催化氧化及其测定  

Electrocatalytic Oxidation and Determination of Rutin by Novel Flowerlike Nano-Co_3O_4 Particles Modified Glassy Carbon Electrode

作　　者：王明艳[1,2] 张东恩[2] 马卫兴[2] 童志伟[2] 许兴友[1,3] 杨绪杰[1] 

机构地区：[1]南京理工大学材料化学实验室,南京210094 [2]淮海工学院化学工程学院,连云港222005 [3]淮阴工学院,淮阴223003

出　　处：《分析化学》2010年第10期1388-1392,共5页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金(No.50873042);江苏省海洋资源开发研究院开放基金(No.JSIMR09B05);淮海工学院自然基金(No.Z2008021)资助项目

摘　　要：采用滴涂法制备了新型花状纳米Co3O4修饰玻碳电极(F-Co3O4-np/GC/CME)。纳米Co3O4的扫描电镜(SEM)表明,纳米Co3O4膜为多孔纳米材料;X-射线衍射光谱(XRD)表明,纳米Co3O4为纯面心立方相尖晶石结构。采用循环伏安法(CV)、计时电量法(CC)、半微分线性伏安法(SDV)研究了芦丁在F-Co3O4-np/GC/CME上的电化学行为及动力学性质。结果表明:芦丁在此修饰电极上有敏锐的氧化还原峰,其氧化峰电流与电位扫描速度(v)呈良好线性关系,表明芦丁在修饰电极上的伏安行为受吸附控制。芦丁的氧化峰电流与其浓度在1.0×10-6～4.5×10-4mol/L范围内呈线性关系;检出限为5.0×10-7mol/L。本方法可用于槐花、红花、金银花、杜仲叶的提取液中芦丁含量的测定,加标回收率为99.5%～100.9%之间;RSD为1.7%～4.5%。A novel flowerlike nano-Co3O4 particles modified glass carbon electrode （F-Co3O4-np/GC/CME） was fabricated by dropwise method.The SEM imagines showed the nano-Co3O4 particles were aggregated into porous form and the XRD spectrum indicated that the nano-Co3O4 particle had pure cubic phase spinel structure.The electrochemical behaviors and kinetic parameters of rutin on F-Co3O4-np/GC/CME were investigated by cyclic voltammetry （CV） ,chronocoulometry （CC） and semi-derivative voltammetry （SDV） .The experimental results showed that the redox peak currents of rutin increased significantly at CME in comparison with those at GCE.The influence of potential scan rate （v） on ipa of rutin at CME was studied and the results indicated that the electrode reaction was adsorptive controlled process.In B-R buffer solution,the oxidation peak currents are proportional to the concentrations of rutin over the range from 1.0×106 to 4.5×104 mol/L and the detection limit is 5.0×107 mol/L.This method has been applied to the determination of rutin in four kinds of Chinese herb medicine extractive samples,the recovery is from 99.5% to 100.9% and RSD is from 1.7% to 4.5% .

关 键 词：修饰电极 四氧化三钴纳米颗粒 芦丁 电催化 

分 类 号：R318.0[医药卫生—生物医学工程]