Dobutamine对心肌背向散射积分的影响  

Influence of Dobutamine on Myocardial Integrated Backscatter

作　　者：陈宇翔[1,2] 钱蕴秋[1,2] 周晓东[1,2] 张军 李军[1,2] 

机构地区：[1]西安市第四军医大学西京医院超声科 [2]解放军第202医院特诊科

出　　处：《中国超声医学杂志》1999年第5期329-331,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的：探讨正性肌力药对心肌背向散射特性的影响。方法：本研究应用背向散射积分联机分析技术，观察８只活体开胸犬静脉灌注多巴酚丁胺前后心肌标化背向散射积分（ＩＢＳ％），背向散射积分周期变异率（ＣＶＩＢ％）及跨壁ＣＶＩＢ％的变化。结果：静脉灌注多巴酚丁胺后，ＣＶＩＢ％明显增加（３７．９±８．９ｖｓ４９．３±１４．２，Ｐ＜０．０５），心内膜下与心外膜下心肌的ＣＶＩＢ％均明显增加，但心外膜下心肌ＣＶＩＢ％增加的幅度较大，表现为跨壁梯度减低（１．５６±０．２１ｖｓ１．１４±０．２５，Ｐ＜０．０１）。ＩＢＳ无明显变化。结论：多巴酚丁胺能够增加正常心肌的背向散射积分周期变异幅度，周期变异的增加主要由心外膜下心肌周期变异增加所致。Objective:To discuss the influence of dobutamine on myocardial integrated backscatter(IBS).Methods:Calibrated myocardial integrated backscatter,cyclic variation of integrated backscatter(CVIB%)and CVIB% transmural gradient were measured with a commercially available system in 8 anesthetized open chest dogs before and after dobutamine infusion.Results:After dobutamine infusion,the CVIB% increased significantly(37 9±8 9 vs 49 3±14 2, P <0 05).CVIB of endocardium and epicardium all increased,the increased extent of epicardium was higher than endocardium showing a decreased CVIB transmural gradient(1 56±0 21 vs 1 14±0 25, P <0 01).The IBS had no significant changes.Conclusion:Dobutamine could increase CVIB of normal myocardium especially of epicardium.

关 键 词：背向散射积分 多巴酚丁胺 心肌 超声波诊断 

分 类 号：R542.204[医药卫生—心血管疾病] R445.1[医药卫生—内科学]