膝关节镜术后舒芬太尼罗哌卡因复合镇痛  

Analgesic Effects of Intraarticular Sufentanil Plus Ropivacaine after Arthroscopic Knee Surgery

作　　者：朱志鹏[1] 邱建新[1] 吴军明[1] 于鹏[1] 肖旺频[1] 

机构地区：[1]浙江省嘉兴市第二医院麻醉科,嘉兴314000

出　　处：《中国中西医结合外科杂志》2010年第5期542-544,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:评价膝关节镜术后关节腔内注射舒芬太尼罗哌卡因混合液的镇痛效果。方法:择期全麻下行膝关节镜手术病人90例,ASAⅠ～Ⅱ级,随机分为3组(n=30):罗哌卡因(R)组、舒芬太尼罗哌卡因(SR)组和生理盐水(S)组。手术结束时,R组关节腔内注射0.45%罗哌卡因20mL,SR组腔内注射5μg舒芬太尼与0.45%罗哌卡因混合液20mL,S组注射等量的生理盐水。结果:与S组比较,R、SR组安静和运动状态下的VAS评分、额外止痛剂的需要量有显著差异(P<0.05或P<0.01);与R组相比,SR组在运动状态下拥有更好的镇痛效果(P<0.05),更少的额外止痛剂的需要量(P<0.01)。结论:膝关节镜术后关节腔内注射舒芬太尼与罗哌卡因混合液有完善的镇痛效果,减少了额外止痛剂的需要量。Objective To evaluate the postoperative analgesic effects of intra-articular sufentanil with ropivacaine following knee arthroscopy. Methods Ninety patients undergoing scheduled arthorscopic knee surgery under general anesthesia, ASA I-II were randomly allocated to 3 groups （n=30）： ropivacaine （R） group, sufentanil plus ropivacaine （SR） group and saline （S） group. Before the operation finished, patient were randomly assigned to 3 groups for double-blind administration of the tested drug： Group R received 0.45% ropivacaine 20 ml intraarticularly, Group SR received sufentanil 5 μg plus 0.45% ropvacaine in 20 ml mixed solution intraarticularly and Group S received 20 ml saline intraarticularly. Results Pain scores and supplementary analgesia were statistically different in the Group R and Group SR in comparison with Group S, but during movement Group SR had better pain control and lesser supplementary analgesia comparing with Group R. Conclusion The combined use of intraarticular sufentanil and ropivacaine in arthoscopic knee surgery can reduce both postoperative pain scores and the use of additional analgesics.

关 键 词：膝关节镜 舒芬太尼 罗哌卡因 术后镇痛 

分 类 号：R614.27[医药卫生—麻醉学]